Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FEK99_RS16335 Genome accession   NZ_CP040309
Coordinates   3306493..3307149 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 21B8     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3301493..3312149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FEK99_RS16295 (FEK99_16770) - 3301493..3302629 (-) 1137 WP_032161583.1 IS30-like element IS30 family transposase -
  FEK99_RS16300 (FEK99_16775) - 3302571..3302765 (-) 195 WP_115801851.1 hypothetical protein -
  FEK99_RS16305 (FEK99_16780) - 3302786..3303067 (-) 282 WP_001303543.1 hypothetical protein -
  FEK99_RS16325 (FEK99_16800) pgsA 3304059..3304607 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FEK99_RS16330 (FEK99_16805) uvrC 3304664..3306496 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FEK99_RS16335 (FEK99_16810) letA 3306493..3307149 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FEK99_RS27935 (FEK99_16815) - 3307291..3307407 (+) 117 WP_001302039.1 hypothetical protein -
  FEK99_RS16340 (FEK99_16820) yecU 3307445..3307621 (+) 177 WP_001302050.1 protein YecU -
  FEK99_RS16345 (FEK99_16825) yecF 3307608..3307832 (+) 225 WP_000106479.1 DUF2594 family protein YecF -
  FEK99_RS16350 (FEK99_16830) sdiA 3307900..3308622 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  FEK99_RS16355 (FEK99_16835) tcyN 3308852..3309604 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FEK99_RS16360 (FEK99_16840) tcyL 3309601..3310269 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  FEK99_RS16365 (FEK99_16845) dcyD 3310284..3311270 (-) 987 WP_001128225.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=321159 FEK99_RS16335 WP_000611328.1 3306493..3307149(-) (letA) [Escherichia coli strain 21B8]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=321159 FEK99_RS16335 WP_000611328.1 3306493..3307149(-) (letA) [Escherichia coli strain 21B8]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482