Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EST51_RS10670 Genome accession   NZ_CP040263
Coordinates   2159844..2160500 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 631     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2154844..2165500
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EST51_RS10640 (EST51_10635) dcyD 2155724..2156710 (+) 987 WP_020232905.1 D-cysteine desulfhydrase -
  EST51_RS10645 (EST51_10640) tcyL 2156725..2157393 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EST51_RS10650 (EST51_10645) tcyN 2157390..2158142 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EST51_RS10655 (EST51_10650) sdiA 2158372..2159094 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  EST51_RS10660 (EST51_10655) yecF 2159161..2159385 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EST51_RS10665 (EST51_10660) yecU 2159372..2159548 (-) 177 WP_000590347.1 protein YecU -
  EST51_RS10670 (EST51_10665) letA 2159844..2160500 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EST51_RS10675 (EST51_10670) uvrC 2160497..2162329 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EST51_RS10680 (EST51_10675) pgsA 2162386..2162934 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EST51_RS10700 (EST51_10695) - 2163927..2164208 (+) 282 WP_071790047.1 hypothetical protein -
  EST51_RS10705 (EST51_10700) - 2164397..2164537 (-) 141 WP_000078920.1 Hok/Gef family protein -
  EST51_RS10710 (EST51_10705) - 2164729..2164989 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=320838 EST51_RS10670 WP_000611328.1 2159844..2160500(+) (letA) [Escherichia coli strain 631]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=320838 EST51_RS10670 WP_000611328.1 2159844..2160500(+) (letA) [Escherichia coli strain 631]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment