Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D4L20_RS05015 Genome accession   NZ_CP032899
Coordinates   1031238..1033022 (+) Length   594 a.a.
NCBI ID   WP_139549727.1    Uniprot ID   -
Organism   Helicobacter pylori strain 478-A-EK1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1026238..1038022
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4L20_RS04985 motB 1027002..1027775 (+) 774 WP_139549723.1 flagellar motor protein MotB -
  D4L20_RS04990 - 1027781..1028218 (+) 438 WP_001875641.1 hypothetical protein -
  D4L20_RS04995 - 1028287..1029948 (+) 1662 WP_139549724.1 ABC transporter permease/substrate-binding protein -
  D4L20_RS05000 - 1029952..1030593 (+) 642 WP_139549725.1 ATP-binding cassette domain-containing protein -
  D4L20_RS05005 - 1030605..1030784 (-) 180 WP_001874585.1 hypothetical protein -
  D4L20_RS05010 - 1030776..1031237 (+) 462 WP_139549726.1 hypothetical protein -
  D4L20_RS05015 uvrC 1031238..1033022 (+) 1785 WP_139549727.1 excinuclease ABC subunit UvrC Machinery gene
  D4L20_RS05020 - 1033033..1034298 (+) 1266 WP_139549728.1 homoserine dehydrogenase -
  D4L20_RS05025 - 1034299..1034643 (+) 345 WP_139549729.1 YraN family protein -
  D4L20_RS05030 trxA 1034735..1035055 (+) 321 WP_120834087.1 thioredoxin -
  D4L20_RS05035 trxB 1035060..1035995 (+) 936 WP_000564429.1 thioredoxin-disulfide reductase -
  D4L20_RS05040 - 1036204..1037025 (+) 822 WP_139549730.1 glycosyltransferase family 25 protein -
  D4L20_RS05045 - 1037241..1037489 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68632.93 Da        Isoelectric Point: 9.7378

>NTDB_id=320069 D4L20_RS05015 WP_139549727.1 1031238..1033022(+) (uvrC) [Helicobacter pylori strain 478-A-EK1]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLS
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHSSSQCVGGMVVYENHAFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPNNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=320069 D4L20_RS05015 WP_139549727.1 1031238..1033022(+) (uvrC) [Helicobacter pylori strain 478-A-EK1]
ATGGCTGATTTATTGTCCAGTTTAAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATTATCGCGCTAGCTTACGAATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAGAATAAAGACAAACTCATCAAGGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCGAGCAATAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAGT
GCTTGCTCTAATGAAGCGCTTAAAGAATTGCAAGAATTTATCTCCCATCAATATTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCTAGCAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAAACTCTTATCGGCG
CTACCATTTGAAAGGCTCTAACGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAACAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTGTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.811

100

0.978

Multiple sequence alignment