Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   E8M05_RS10155 Genome accession   NZ_CP039457
Coordinates   1944590..1945897 (-) Length   435 a.a.
NCBI ID   WP_003066569.1    Uniprot ID   E0PG58
Organism   Streptococcus pasteurianus strain WUSP067     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1939590..1950897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS10100 (E8M05_10090) rsgA 1939862..1940734 (-) 873 WP_013852268.1 ribosome small subunit-dependent GTPase A -
  E8M05_RS10115 (E8M05_10105) - 1941180..1941407 (-) 228 WP_003066551.1 hypothetical protein -
  E8M05_RS11660 comD/comD3 1941539..1941853 (-) 315 WP_003066552.1 GHKL domain-containing protein Regulator
  E8M05_RS11335 comE/comE2 1942255..1942476 (-) 222 WP_003066558.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  E8M05_RS10125 (E8M05_10115) - 1942448..1942810 (-) 363 WP_061100337.1 bacteriocin immunity protein -
  E8M05_RS10130 (E8M05_10120) - 1942861..1943013 (-) 153 WP_231729917.1 hypothetical protein -
  E8M05_RS10135 (E8M05_10125) - 1943362..1943673 (-) 312 WP_048791097.1 bacteriocin immunity protein -
  E8M05_RS10150 (E8M05_10140) - 1944431..1944568 (+) 138 WP_003066566.1 hypothetical protein -
  E8M05_RS10155 (E8M05_10145) comD/comD1 1944590..1945897 (-) 1308 WP_003066569.1 sensor histidine kinase Regulator
  E8M05_RS10160 (E8M05_10150) comE/comE1 1945905..1946636 (-) 732 WP_058692509.1 response regulator transcription factor Regulator
  E8M05_RS10165 (E8M05_10155) - 1946653..1946937 (-) 285 WP_231729918.1 LytTR family DNA-binding domain-containing protein -
  E8M05_RS11665 (E8M05_10160) - 1947180..1947788 (-) 609 WP_136596476.1 hypothetical protein -
  E8M05_RS10175 (E8M05_10165) - 1947960..1948256 (-) 297 WP_003066579.1 bacteriocin immunity protein -
  E8M05_RS10180 (E8M05_10170) - 1948256..1948474 (-) 219 WP_003066580.1 Blp family class II bacteriocin -
  E8M05_RS11900 - 1948666..1948785 (-) 120 WP_253066439.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  E8M05_RS11670 - 1948782..1949102 (-) 321 WP_230321658.1 CPBP family intramembrane glutamic endopeptidase -
  E8M05_RS11675 - 1949159..1949338 (-) 180 WP_003066584.1 hypothetical protein -
  E8M05_RS10190 (E8M05_10180) - 1949508..1949819 (-) 312 WP_003066586.1 hypothetical protein -
  E8M05_RS10195 (E8M05_10185) - 1949908..1950138 (-) 231 WP_061100340.1 bacteriocin -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 51212.82 Da        Isoelectric Point: 6.0108

>NTDB_id=317862 E8M05_RS10155 WP_003066569.1 1944590..1945897(-) (comD/comD1) [Streptococcus pasteurianus strain WUSP067]
MSDYLSELAYYPVIMLIYSNVRGEKLKLWEIVTIAVAFFVIDFTWFYTIIGRILILMFLSYLRDKTLPFSLYVFYGSIPW
VIESAFKRIISFFIIPFFNFSYTDLDKNNLLFVIVEFSIILMYFMMVQLFKINFQTFIALSEIKNLRKKLIFTDLTMMFY
YVMIEFLTGMEVYGGVPNLVYRQWLVVLYFTFFTLMLFYMNRSYQNWLEKEVSLAREQELHSLSVYSKQIEGLYEELRAF
RHDYANILASLKEGIDQNDMSMVRNIYNAVLEDSGKFIQHSRFNIGRLTNIDNDAIKSLLSAEFLEAESHHIEVELEVKD
KIGTPDIPLLDYVRLVSILCDNAIEAAIEAEKPAMIIACFYQGDDYLLIIDNTTKEERVPVELIYQKNYSSKGFGRGVGL
KTVNQMLKKYPNMSVQTSSKNYHFRQTIRIKKSFD

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=317862 E8M05_RS10155 WP_003066569.1 1944590..1945897(-) (comD/comD1) [Streptococcus pasteurianus strain WUSP067]
ATGAGTGATTATCTAAGTGAACTAGCTTACTATCCTGTGATTATGTTGATTTACTCTAATGTTAGAGGAGAAAAACTGAA
ATTGTGGGAAATAGTAACGATAGCTGTTGCTTTCTTCGTCATTGATTTTACATGGTTTTATACTATTATCGGTCGTATTT
TAATATTGATGTTTCTATCTTATTTGAGAGATAAAACCTTGCCCTTTTCTCTATACGTATTTTATGGGAGTATTCCATGG
GTTATAGAGAGTGCTTTTAAAAGAATTATTAGTTTCTTCATTATTCCATTTTTTAATTTTAGTTATACCGATTTAGATAA
AAATAATTTATTATTTGTCATTGTAGAATTTTCAATAATTCTGATGTATTTTATGATGGTGCAGTTGTTTAAAATTAACT
TTCAAACTTTTATTGCACTAAGTGAGATAAAAAATCTACGAAAGAAACTAATATTTACAGATTTAACAATGATGTTTTAC
TATGTCATGATTGAATTTTTAACAGGTATGGAAGTTTATGGTGGTGTCCCAAACTTGGTTTATCGCCAATGGTTGGTGGT
TCTCTATTTCACTTTCTTCACTTTAATGTTGTTTTATATGAATCGCTCTTATCAAAATTGGCTGGAGAAAGAAGTATCGT
TAGCGCGGGAGCAAGAACTGCATTCTTTGTCGGTATATAGCAAGCAAATCGAAGGCTTATATGAGGAACTAAGAGCTTTT
CGTCATGATTATGCTAATATCTTAGCGAGTTTAAAAGAGGGAATCGACCAAAATGATATGAGTATGGTGAGGAATATTTA
TAATGCCGTTTTAGAGGATTCTGGAAAGTTTATTCAGCATAGTCGCTTCAATATTGGACGATTGACTAATATTGATAATG
ATGCGATAAAAAGCCTTTTATCAGCTGAATTTTTAGAAGCGGAATCTCATCATATTGAGGTAGAATTAGAAGTTAAAGAT
AAAATTGGAACTCCAGATATTCCTTTGTTAGATTATGTGCGGCTCGTCTCCATTTTATGTGACAATGCGATTGAAGCGGC
TATTGAAGCTGAAAAGCCTGCCATGATTATTGCTTGTTTCTATCAAGGGGATGACTATTTACTAATTATAGATAACACCA
CAAAAGAAGAGCGAGTTCCTGTGGAATTGATTTACCAGAAGAATTATTCAAGTAAGGGCTTTGGACGAGGTGTTGGTCTT
AAAACGGTTAACCAGATGTTGAAAAAGTATCCAAATATGTCGGTACAAACATCAAGCAAGAATTATCATTTCAGACAAAC
AATACGAATCAAAAAATCATTCGACTGA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(330-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PG58

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

76.724

53.333

0.409