Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   E8M05_RS02500 Genome accession   NZ_CP039457
Coordinates   448443..449087 (+) Length   214 a.a.
NCBI ID   WP_013851527.1    Uniprot ID   F5X535
Organism   Streptococcus pasteurianus strain WUSP067     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 443443..454087
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS02480 (E8M05_02475) - 444030..444767 (+) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  E8M05_RS02485 (E8M05_02480) pknB 444767..446647 (+) 1881 WP_003063531.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  E8M05_RS02490 (E8M05_02485) liaF 446742..447437 (+) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  E8M05_RS02495 (E8M05_02490) - 447434..448459 (+) 1026 WP_013851526.1 sensor histidine kinase -
  E8M05_RS02500 (E8M05_02495) vraR 448443..449087 (+) 645 WP_013851527.1 response regulator transcription factor Regulator
  E8M05_RS02505 (E8M05_02500) - 449205..450605 (+) 1401 WP_069789204.1 Cof-type HAD-IIB family hydrolase -
  E8M05_RS02510 (E8M05_02505) - 450605..450961 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  E8M05_RS02515 (E8M05_02510) cysK 451074..452003 (-) 930 WP_013851529.1 cysteine synthase A -
  E8M05_RS02520 (E8M05_02515) - 452107..452733 (-) 627 WP_003063547.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23953.74 Da        Isoelectric Point: 4.6633

>NTDB_id=317798 E8M05_RS02500 WP_013851527.1 448443..449087(+) (vraR) [Streptococcus pasteurianus strain WUSP067]
MTQKIKIILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=317798 E8M05_RS02500 WP_013851527.1 448443..449087(+) (vraR) [Streptococcus pasteurianus strain WUSP067]
ATGACCCAGAAAATTAAAATTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGCTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTCGGCGAAGCTGGAAATGGTTTAGACGGTATTAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCGACATTGAAGCTTCTGGAAGAATGGAAAGAAGCTAAG
ATTCTTGTCTTAACATCTTACCTTGATAATGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAACCAAACTATTGCTGATGAGTTATTTATCTCACTAAAGACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTCGATGACCGTACACAAGCAGTCGTTTACGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5X535

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.942

96.262

0.5
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.397

Multiple sequence alignment