Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   MGAS27961_RS09735 Genome accession   NZ_CP032665
Coordinates   53781..53882 (+) Length   33 a.a.
NCBI ID   WP_391592286.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS27961     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 48781..58882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS27961_RS00315 (MGAS27961_00315) purK 48852..49925 (+) 1074 WP_021340856.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  MGAS27961_RS00320 (MGAS27961_00320) - 49927..51345 (+) 1419 WP_011888524.1 hypothetical protein -
  MGAS27961_RS00325 (MGAS27961_00325) purB 51365..52657 (+) 1293 WP_011284409.1 adenylosuccinate lyase -
  MGAS27961_RS00330 (MGAS27961_00330) comR 52788..53699 (+) 912 WP_060383922.1 transcriptional regulator Rgg4/ComR Regulator
  MGAS27961_RS09735 comS 53781..53882 (+) 102 WP_391592286.1 quorum-sensing system DWW-type pheromone Regulator
  MGAS27961_RS00335 (MGAS27961_00335) ruvB 53929..54927 (+) 999 WP_011054100.1 Holliday junction branch migration DNA helicase RuvB -
  MGAS27961_RS00340 (MGAS27961_00340) - 55065..55502 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  MGAS27961_RS00345 (MGAS27961_00345) - 55525..55926 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  MGAS27961_RS00350 (MGAS27961_00350) - 55923..57698 (+) 1776 WP_011284411.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 33 a.a.        Molecular weight: 4108.95 Da        Isoelectric Point: 10.2879

>NTDB_id=317779 MGAS27961_RS09735 WP_391592286.1 53781..53882(+) (comS) [Streptococcus pyogenes strain MGAS27961]
MHVKKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 102 bp        

>NTDB_id=317779 MGAS27961_RS09735 WP_391592286.1 53781..53882(+) (comS) [Streptococcus pyogenes strain MGAS27961]
ATCCATGTTAAAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGC
TGTTGACTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

87.879

0.879

  comS Streptococcus pyogenes MGAS315

41.379

87.879

0.364


Multiple sequence alignment