Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   CBUG_RS10165 Genome accession   NC_011527
Coordinates   1919400..1920326 (+) Length   308 a.a.
NCBI ID   WP_012570515.1    Uniprot ID   -
Organism   Coxiella burnetii CbuG_Q212     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1914400..1925326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CBUG_RS10125 (CbuG_1998) - 1915042..1915314 (-) 273 WP_010957319.1 hypothetical protein -
  CBUG_RS10130 (CbuG_1999) - 1915455..1915709 (+) 255 WP_005769716.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
  CBUG_RS10135 (CbuG_2000) - 1915709..1915984 (+) 276 WP_005769718.1 Txe/YoeB family addiction module toxin -
  CBUG_RS10140 (CbuG_2001) - 1915957..1916442 (-) 486 WP_005769725.1 dihydrofolate reductase -
  CBUG_RS10145 (CbuG_2002) - 1916439..1917242 (-) 804 WP_010958584.1 epoxyqueuosine reductase QueH -
  CBUG_RS10150 (CbuG_2003) - 1917438..1917725 (+) 288 WP_032138540.1 acylphosphatase -
  CBUG_RS10155 (CbuG_2004) gmhB 1917701..1918255 (-) 555 WP_005769732.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -
  CBUG_RS10160 (CbuG_2005) fmt 1918268..1919212 (-) 945 WP_010958586.1 methionyl-tRNA formyltransferase -
  CBUG_RS10165 (CbuG_2006) dprA 1919400..1920326 (+) 927 WP_012570515.1 DNA-processing protein DprA Machinery gene
  CBUG_RS10170 (CbuG_2007) - 1920323..1920802 (+) 480 WP_010958588.1 DUF494 domain-containing protein -
  CBUG_RS10175 (CbuG_2008) topA 1920805..1923102 (+) 2298 WP_012570516.1 type I DNA topoisomerase -
  CBUG_RS10180 (CbuG_2009) - 1923109..1923279 (-) 171 WP_010958590.1 hypothetical protein -
  CBUG_RS10185 (CbuG_2010) purE 1923310..1923810 (+) 501 WP_005769750.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  CBUG_RS10190 (CbuG_2011) - 1923813..1924373 (+) 561 WP_012570517.1 L-threonylcarbamoyladenylate synthase -
  CBUG_RS12810 - 1924423..1924542 (+) 120 Protein_2076 hypothetical protein -
  CBUG_RS10195 (CbuG_2012) - 1924816..1924956 (+) 141 WP_012570518.1 hypothetical protein -

Sequence

Protein


Download         Length: 308 a.a.        Molecular weight: 33002.19 Da        Isoelectric Point: 7.5121

>NTDB_id=31774 CBUG_RS10165 WP_012570515.1 1919400..1920326(+) (dprA) [Coxiella burnetii CbuG_Q212]
MQLPFNALLFFAMPNSQLDPEWTTAPNHHILTLDHPSYPTLLKEIPDPPKKLYIMGDPLILNQPQFAIVGSRNPTVTGCE
IAQEMAEKLVQAGFHITSGLALGIDAASHRGALKAGGQTIAVLGSGLTNIYPRRHHRLAEQISQKGALVSEFSLTMPPLP
TNFPRRNRIISGLSLGTLVVEATLGSGSLITAKLAAEQNREVFAIPGSIRNPLSQGCHALIKEGAKLVDSIGDIIAELSY
EATGASAPIQALDKNEHKLLECIGFEVTSIDQLIARSGFSASIVASLLLRIELQGYIKSTPGGVIRVK

Nucleotide


Download         Length: 927 bp        

>NTDB_id=31774 CBUG_RS10165 WP_012570515.1 1919400..1920326(+) (dprA) [Coxiella burnetii CbuG_Q212]
TTGCAACTTCCCTTCAATGCACTATTATTTTTCGCCATGCCAAATTCTCAATTAGACCCAGAATGGACGACAGCGCCGAA
CCACCATATTTTGACGCTCGATCATCCCTCCTACCCTACTTTATTGAAGGAAATCCCCGATCCGCCCAAAAAGCTCTACA
TCATGGGTGACCCTTTGATATTAAATCAGCCGCAATTTGCCATCGTCGGCAGCCGTAATCCAACCGTCACCGGCTGCGAA
ATCGCACAAGAAATGGCAGAGAAACTCGTTCAAGCTGGTTTTCACATCACCAGCGGCCTTGCACTTGGCATCGATGCCGC
AAGTCACCGCGGGGCTTTAAAAGCAGGAGGCCAAACCATAGCCGTACTCGGCAGCGGCTTAACTAACATATATCCTCGAC
GCCACCACCGTCTGGCGGAACAAATTTCCCAAAAAGGCGCCCTCGTCTCAGAATTCTCGCTAACCATGCCGCCACTCCCC
ACCAACTTCCCTCGCCGCAACCGCATCATCAGCGGATTAAGCCTCGGTACGCTCGTGGTGGAAGCTACCCTTGGCTCAGG
CTCTCTGATCACCGCGAAATTAGCCGCCGAACAAAACCGGGAAGTTTTCGCCATCCCGGGTTCAATCCGAAACCCTCTTT
CTCAGGGATGCCATGCTCTCATCAAAGAGGGCGCTAAACTGGTTGATTCTATAGGGGATATTATTGCAGAATTGAGTTAT
GAGGCTACGGGCGCTAGCGCCCCGATTCAAGCACTTGATAAGAATGAACACAAACTGTTAGAGTGCATCGGATTTGAGGT
CACTTCCATTGATCAACTGATCGCTCGAAGTGGCTTTTCGGCTTCCATCGTAGCTTCGTTATTGTTAAGGATAGAATTGC
AAGGCTACATTAAATCAACACCTGGCGGTGTTATACGAGTGAAGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(25-229)

DprA winged helix domain (DprA_WH)

(245-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Legionella pneumophila strain ERS1305867

54.266

95.13

0.516
  dprA Vibrio cholerae strain A1552

49.164

97.078

0.477
  dprA Vibrio campbellii strain DS40M4

47.712

99.351

0.474
  dprA Glaesserella parasuis strain SC1401

45.277

99.675

0.451
  dprA Acinetobacter baumannii D1279779

44.71

95.13

0.425
  dprA Acinetobacter baumannii strain A118

44.218

95.455

0.422
  dprA Acinetobacter baylyi ADP1

43.051

95.779

0.412
  dprA Haemophilus influenzae Rd KW20

55.505

70.779

0.393

Multiple sequence alignment