Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E4311_RS13500 Genome accession   NZ_CP039403
Coordinates   2717408..2718064 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 382634_2f     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2712408..2723064
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4311_RS13470 (E4311_13470) yecA 2713659..2714324 (-) 666 WP_000847885.1 UPF0149 family protein YecA -
  E4311_RS13490 (E4311_13490) pgsA 2714974..2715522 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E4311_RS13495 (E4311_13495) uvrC 2715579..2717411 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E4311_RS13500 (E4311_13500) letA 2717408..2718064 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E4311_RS13505 (E4311_13505) yecU 2718360..2718536 (+) 177 WP_001307856.1 protein YecU -
  E4311_RS13510 (E4311_13510) yecF 2718523..2718747 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  E4311_RS13515 (E4311_13515) sdiA 2718815..2719537 (-) 723 WP_136479082.1 transcriptional regulator SdiA -
  E4311_RS13520 (E4311_13520) tcyN 2719767..2720519 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E4311_RS13525 (E4311_13525) tcyL 2720516..2721184 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  E4311_RS13530 (E4311_13530) dcyD 2721199..2722185 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=317562 E4311_RS13500 WP_000611328.1 2717408..2718064(-) (letA) [Escherichia coli strain 382634_2f]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=317562 E4311_RS13500 WP_000611328.1 2717408..2718064(-) (letA) [Escherichia coli strain 382634_2f]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482