Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   D7D53_RS03175 Genome accession   NZ_CP032621
Coordinates   636354..638594 (+) Length   746 a.a.
NCBI ID   WP_120770099.1    Uniprot ID   A0A387AZL4
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 631354..643594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS03140 (D7D53_03140) frr 631491..632048 (+) 558 WP_001262225.1 ribosome recycling factor -
  D7D53_RS03145 (D7D53_03145) cvfB 632108..632962 (+) 855 WP_120164223.1 RNA-binding virulence regulatory protein CvfB -
  D7D53_RS03150 (D7D53_03150) - 632971..633186 (+) 216 WP_120164222.1 YozE family protein -
  D7D53_RS03155 (D7D53_03155) - 633271..634266 (+) 996 WP_120770096.1 PhoH family protein -
  D7D53_RS03160 (D7D53_03160) ald 634323..635435 (-) 1113 WP_120770097.1 alanine dehydrogenase -
  D7D53_RS03165 (D7D53_03165) - 635570..635653 (+) 84 Protein_601 N-acetyltransferase -
  D7D53_RS03170 (D7D53_03170) comEA/celA/cilE 635720..636370 (+) 651 WP_120770098.1 helix-hairpin-helix domain-containing protein Machinery gene
  D7D53_RS03175 (D7D53_03175) comEC/celB 636354..638594 (+) 2241 WP_120770099.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  D7D53_RS03180 (D7D53_03180) infC 638814..639344 (+) 531 WP_000848180.1 translation initiation factor IF-3 -
  D7D53_RS03185 (D7D53_03185) rpmI 639377..639577 (+) 201 WP_001125943.1 50S ribosomal protein L35 -
  D7D53_RS03190 (D7D53_03190) rplT 639629..639988 (+) 360 WP_120770100.1 50S ribosomal protein L20 -
  D7D53_RS03195 (D7D53_03195) - 640047..640427 (+) 381 WP_000157153.1 VOC family protein -
  D7D53_RS03200 (D7D53_03200) - 640676..641476 (+) 801 WP_120770101.1 dihydroorotate dehydrogenase electron transfer subunit -
  D7D53_RS03205 (D7D53_03205) - 641439..642425 (+) 987 WP_162927865.1 dihydroorotate dehydrogenase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 84737.11 Da        Isoelectric Point: 9.4281

>NTDB_id=317181 D7D53_RS03175 WP_120770099.1 636354..638594(+) (comEC/celB) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MLQWIKNFPMPLIYLSFLLFWLYYAIFSASYLALLGFVFLLVSLFFQFPWKPASKVLVICGIFGFWFLFQNWQQSQASQN
LTDSVERVRILPDTIKVNGDSLSFRGKSDGRIFQVYYKLQSENEKEQFQALTDLHEIELEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKKIQSLQKVGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSILYAGLTGFSTSVIRSLLQKLLAQHGVKGFDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
IFALSFLYPVIQLNFIFEWLEGMIRLVSQVASRPLVFGQPNACLLILLLISLALVYDLRKNIKRLAVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEKWQEKATTSNAQRTLIPYLKSRGVSKIDQLILTNTDK
EYVGDLLEVTKAFHVAEILVSKGSLKQKEFVVELQATQTKVRSLTVGEKLTIFGSQLEVLSPRKIGDGGHEDSLVLYGKL
LDKNFLFTGNLEEKGEKALLKQYPDLEVDVLKAGQHGSKKSSSSAFLEQLKQEMTLISVGKNNRTKLPHQETLTRLEDIN
SKVYRTDQQGAIRFKGWKNWKIETVG

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=317181 D7D53_RS03175 WP_120770099.1 636354..638594(+) (comEC/celB) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGTTACAGTGGATTAAGAATTTCCCCATGCCCCTAATTTACCTGAGTTTTCTGTTATTTTGGCTTTACTACGCTATTTT
CTCAGCATCCTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCAGTCTTTTTTTCCAATTTCCTTGGAAACCTGCTA
GCAAAGTTCTAGTGATTTGTGGAATCTTTGGTTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAGAAT
TTGACGGATTCTGTTGAAAGGGTACGGATTTTGCCTGACACTATTAAGGTAAATGGCGATAGTCTGTCCTTTCGTGGTAA
GTCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGAATGAAAAAGAGCAATTTCAAGCCTTAACAGACC
TTCATGAGATAGAACTAGAAGGAAAACTTTCGGAGCCAGAGGGGCAGAGGAATTTTGGTGGATTTAACTATCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGGTTGGCAGTTGGGATATAGG
AGAAAATCTGTCCAGTTTACGCCGTAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CGGGTCTTCTATTAGGACATCTGGACACAGATTTTGAGGAGATGAATGAGCTGTATTCCAGTCTAGGAATTATTCACCTT
TTTGCCTTGTCGGGTATGCAGGTAGGATTTTTCATGGATGGATTTAAGAAACTACTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACCTATCCCTTTTCCATTCTCTATGCTGGTCTGACAGGATTTTCAACTTCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTTGATAATTTTGCCTTGACGGTCCTTGTCCTATTTATCATT
ATGCCTAACTTTTTCCTGACTGCAGGAGGAGTTTTGTCATGTGCTTATGCTTTTATCTTGACCATGACCAGCAAAGAAGG
AGAAGGCCTCAAGGCTGTTGCTAGAGAAAGTCTAGTCATTTCCTTGGGAATATTACCCATCCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGGTCTTCTTACCGCTCTTATCTATC
ATATTTGCCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAATTTTATCTTTGAATGGTTGGAGGGAATGATTCGCTTGGT
GTCGCAGGTGGCAAGTAGGCCTCTGGTCTTTGGACAACCCAATGCATGCCTTTTAATCCTATTGTTAATTTCCTTGGCTT
TAGTTTATGATTTGAGGAAAAACATTAAAAGGCTAGCAGTATTGAGCTTATTGATTACAGGTCTCTTTTTCCTGACCAAG
TATCCACTGGAAAATGAAATTACCATGCTGGATGTGGGGCAAGGGGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGCAAGGCAGAATCTGATAAGAAAATCGAAAAATGGCAAGAAAAGGCGACGACCAGTAATG
CCCAGCGAACCTTGATACCCTATCTCAAAAGTCGCGGAGTATCCAAGATTGACCAGCTAATTTTGACCAATACGGACAAG
GAATATGTTGGAGATTTGTTGGAGGTGACCAAGGCTTTCCATGTAGCGGAGATTTTAGTGTCAAAAGGTAGTTTGAAACA
GAAGGAATTTGTGGTAGAACTACAGGCAACTCAAACCAAGGTGCGCAGTTTGACAGTAGGAGAGAAGTTGACAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATTGGAGATGGAGGTCATGAAGATTCCCTGGTTTTGTATGGAAAACTC
TTGGATAAAAACTTTCTTTTCACAGGAAATTTGGAGGAGAAGGGGGAGAAGGCATTGCTGAAGCAGTATCCTGACCTAGA
AGTGGATGTTTTGAAAGCTGGCCAACATGGCTCTAAAAAATCATCAAGTTCAGCCTTTTTAGAACAGCTCAAACAAGAGA
TGACCCTCATCTCAGTTGGAAAGAACAATCGAACGAAACTCCCCCATCAGGAAACCTTGACACGACTAGAAGATATCAAT
AGCAAAGTTTACCGAACTGATCAGCAAGGAGCTATACGCTTTAAAGGGTGGAAAAATTGGAAAATCGAAACGGTTGGTTA
A

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(31-177)

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-692)

Competence protein (Competence)

(216-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387AZL4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

92.886

99.866

0.928
  comEC/celB Streptococcus mitis NCTC 12261

92.359

100

0.924
  comEC/celB Streptococcus pneumoniae TIGR4

90.738

99.866

0.906
  comEC/celB Streptococcus pneumoniae Rx1

90.067

99.866

0.899
  comEC/celB Streptococcus pneumoniae D39

90.067

99.866

0.899
  comEC/celB Streptococcus pneumoniae R6

90.067

99.866

0.899
  comEC Lactococcus lactis subsp. cremoris KW2

45.074

99.33

0.448

Multiple sequence alignment