Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   D7D53_RS00715 Genome accession   NZ_CP032621
Coordinates   165528..166217 (+) Length   229 a.a.
NCBI ID   WP_033686437.1    Uniprot ID   A0A387AVS9
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 160528..171217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS00690 (D7D53_00690) gpsB 160649..160978 (+) 330 WP_000146534.1 cell division regulator GpsB -
  D7D53_RS00700 (D7D53_00700) - 161464..162621 (+) 1158 WP_120769809.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  D7D53_RS00705 (D7D53_00705) mapZ 162634..164016 (+) 1383 WP_120769810.1 cell division site-positioning protein MapZ -
  D7D53_RS00710 (D7D53_00710) gndA 164092..165516 (+) 1425 WP_000158778.1 NADP-dependent phosphogluconate dehydrogenase -
  D7D53_RS00715 (D7D53_00715) covR 165528..166217 (+) 690 WP_033686437.1 response regulator transcription factor Regulator
  D7D53_RS00720 (D7D53_00720) cbpJ 166318..167328 (+) 1011 WP_120769811.1 choline-binding protein CbpJ -
  D7D53_RS00725 (D7D53_00725) cbpC 167346..168365 (+) 1020 WP_120769812.1 choline-binding protein CbpC -
  D7D53_RS00730 (D7D53_00730) mvk 168488..169366 (+) 879 WP_120769813.1 mevalonate kinase -
  D7D53_RS00735 (D7D53_00735) mvaD 169348..170301 (+) 954 WP_120769814.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26785.91 Da        Isoelectric Point: 8.0259

>NTDB_id=317172 D7D53_RS00715 WP_033686437.1 165528..166217(+) (covR) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MGKRILLLEKERNLAHFLSLELQKEQYRVDQVEEGQKALSMALQTDYDLILLNARLGDMTAQDFADKLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDNLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=317172 D7D53_RS00715 WP_033686437.1 165528..166217(+) (covR) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAAAGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAAAAAGAGCAATA
CCGAGTTGATCAGGTTGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGACTTGATTTTATTGAATG
CTCGTCTGGGGGATATGACAGCCCAGGATTTTGCAGATAAGCTCAGTCGGACTAAGCCAGCCTCAGTTATCATGGTCTTG
GACCATCGTGAAGAATTGCAAGATCAGATTGAAACAATCCAACGCTTTGCCGTTTCTTACATCTATAAGCCGGTTATTAT
TGACAATTTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTTC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTTTGACTCGT
CGTGAGTATGACCTCTTGGCTACTCTTATGGGAAGCAAGAAAGTTCTGACTCGTGAGCAGTTGTTGGAAAGTGTCTGGAA
GTATGAAAGTGCGACCGAAACAAATATCGTGGATGTCTATATTCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACAGTTCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387AVS9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment