Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   D7D50_RS00475 Genome accession   NZ_CP032620
Coordinates   72656..73954 (-) Length   432 a.a.
NCBI ID   WP_120701185.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 67656..78954
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS00465 (D7D50_00465) hpf 71355..71900 (-) 546 WP_023022375.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  D7D50_RS00470 (D7D50_00470) - 71988..72593 (-) 606 WP_227877749.1 ComF family protein -
  D7D50_RS00475 (D7D50_00475) comFA/cflA 72656..73954 (-) 1299 WP_120701185.1 DEAD/DEAH box helicase Machinery gene
  D7D50_RS00480 (D7D50_00480) - 74010..74642 (+) 633 WP_023027744.1 YigZ family protein -
  D7D50_RS00485 (D7D50_00485) cysK 74734..75663 (+) 930 WP_120701186.1 cysteine synthase A -
  D7D50_RS00490 (D7D50_00490) - 75715..76083 (-) 369 WP_120701187.1 S1 RNA-binding domain-containing protein -
  D7D50_RS00495 (D7D50_00495) - 76080..77486 (-) 1407 WP_120701188.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  D7D50_RS00500 (D7D50_00500) - 77531..78163 (-) 633 WP_023022361.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49761.22 Da        Isoelectric Point: 9.4826

>NTDB_id=317102 D7D50_RS00475 WP_120701185.1 72656..73954(-) (comFA/cflA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MKVEDCYGRLFTQEQLEVELLGQAQELPAMVEEKTGLFCNRCGTKIDKSKWKLQIGSYYCRACIQLGRVRSDQVLYYFLQ
QAFPQEEVLRWQGSLTPFQSRVSQELVQSLTDRKPMMVHAVTGAGKTEMMYQVVAEVIKKGRCVCIATPRIDVCIELYKR
MTKDFSCPITLLHGDSEAYFRTPLVISTTHQLLKFYQAFDLLIIDEVDAFPFVDNPVLYHAVSNAVTKNGKLIYLTATST
KELDKKVKKQEINRVSLPRRFHGNPLVIPRKVWLKDLRKKVEKKQVPGKLLRLIKEQRKTSFPLILFVSEIELGEKLLNL
LRQNFKDEIIELVTSKTENRLELVEKFRNQEITILVSTTILERGVTFPKVDVFVIEANHRLFTKSTLVQIAGRVGRSMER
PTGELLFLAEGTSQEMTQAIKEIKEMNREAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=317102 D7D50_RS00475 WP_120701185.1 72656..73954(-) (comFA/cflA) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGAAAGTTGAAGATTGTTATGGAAGGTTGTTCACCCAAGAACAACTAGAGGTGGAACTGCTTGGACAAGCCCAAGAACT
GCCAGCTATGGTAGAGGAAAAGACGGGCTTGTTTTGTAATCGGTGTGGGACTAAGATTGATAAAAGCAAATGGAAACTAC
AGATAGGAAGCTACTATTGTAGAGCCTGCATTCAATTAGGAAGAGTTAGGAGCGACCAAGTACTCTATTACTTTCTCCAG
CAAGCCTTTCCGCAGGAAGAAGTCCTAAGATGGCAGGGGAGCTTGACGCCATTTCAAAGTCGGGTTTCTCAAGAGTTGGT
TCAATCCTTAACAGATAGAAAGCCTATGATGGTACACGCAGTTACAGGAGCAGGTAAAACGGAAATGATGTACCAAGTGG
TGGCGGAAGTGATAAAAAAGGGGAGATGTGTTTGCATTGCTACACCAAGGATTGACGTGTGTATTGAATTATATAAGCGA
ATGACAAAGGACTTTTCCTGCCCCATCACGTTGTTGCACGGTGATTCAGAAGCTTATTTCCGAACGCCTCTCGTCATATC
CACCACACATCAACTACTAAAATTTTATCAAGCTTTTGACCTCCTCATCATCGATGAAGTCGATGCCTTTCCTTTTGTTG
ATAACCCTGTTCTCTACCATGCCGTTTCAAATGCCGTAACCAAGAATGGAAAGCTCATCTATTTGACAGCTACCTCAACA
AAAGAGTTAGATAAAAAGGTCAAAAAACAGGAAATAAACCGCGTTAGCCTACCCAGACGCTTTCACGGAAACCCTCTAGT
AATTCCTAGAAAAGTATGGCTAAAAGATCTACGAAAGAAAGTAGAAAAGAAGCAAGTACCAGGGAAGTTACTCAGACTAA
TAAAGGAGCAACGAAAAACAAGCTTTCCACTGATCTTATTTGTATCAGAGATTGAATTAGGAGAAAAGCTCCTTAACCTC
TTAAGACAGAACTTCAAGGATGAAATCATCGAACTGGTGACCTCTAAAACAGAAAATAGGTTAGAACTGGTAGAAAAATT
TCGCAACCAAGAAATTACAATCCTTGTTTCAACGACAATCCTGGAAAGGGGAGTTACCTTCCCTAAAGTAGATGTGTTTG
TGATTGAGGCCAATCATCGGCTGTTCACTAAGAGCACCCTGGTTCAAATCGCTGGTCGTGTAGGAAGAAGTATGGAAAGA
CCCACAGGCGAATTACTTTTTCTAGCAGAAGGAACCAGCCAAGAAATGACACAAGCCATTAAAGAAATAAAAGAAATGAA
TCGGGAGGCAGGATTTTGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(95-238)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

62.587

100

0.627
  comFA/cflA Streptococcus pneumoniae Rx1

62.125

100

0.623
  comFA/cflA Streptococcus pneumoniae D39

62.125

100

0.623
  comFA/cflA Streptococcus pneumoniae R6

62.125

100

0.623
  comFA/cflA Streptococcus pneumoniae TIGR4

62.125

100

0.623
  comFA/cflA Streptococcus mitis SK321

62.125

100

0.623
  comFA Lactococcus lactis subsp. cremoris KW2

52.792

91.204

0.481
  comFA Latilactobacillus sakei subsp. sakei 23K

37.931

100

0.382

Multiple sequence alignment