Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E1950_RS08155 Genome accession   NZ_CP039162
Coordinates   1633527..1634789 (-) Length   420 a.a.
NCBI ID   WP_000472302.1    Uniprot ID   P63789
Organism   Staphylococcus aureus strain Lr12     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1628527..1639789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1950_RS08130 (E1950_08295) - 1628725..1629393 (-) 669 WP_000805951.1 uroporphyrinogen-III synthase -
  E1950_RS08135 (E1950_08300) hemC 1629415..1630341 (-) 927 WP_001230232.1 hydroxymethylbilane synthase -
  E1950_RS08140 (E1950_08305) ccsA 1630383..1631198 (-) 816 WP_001157329.1 cytochrome c biogenesis protein -
  E1950_RS08145 (E1950_08310) hemA 1631220..1632566 (-) 1347 WP_000545451.1 glutamyl-tRNA reductase -
  E1950_RS08150 (E1950_08315) yihA 1632783..1633373 (-) 591 WP_000867697.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E1950_RS08155 (E1950_08320) clpX 1633527..1634789 (-) 1263 WP_000472302.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E1950_RS08160 (E1950_08325) tig 1634940..1636241 (-) 1302 WP_000127573.1 trigger factor -
  E1950_RS08165 (E1950_08330) - 1636289..1636399 (-) 111 WP_001790560.1 hypothetical protein -
  E1950_RS08170 (E1950_08335) - 1636404..1637333 (-) 930 WP_001280022.1 hypothetical protein -
  E1950_RS08175 (E1950_08340) - 1637352..1637960 (-) 609 WP_000032657.1 NUDIX domain-containing protein -
  E1950_RS08180 (E1950_08350) rplT 1638102..1638458 (-) 357 WP_001138360.1 50S ribosomal protein L20 -
  E1950_RS08185 (E1950_08355) rpmI 1638505..1638705 (-) 201 WP_001125540.1 50S ribosomal protein L35 -
  E1950_RS08190 (E1950_08360) infC 1638734..1639261 (-) 528 WP_001791162.1 translation initiation factor IF-3 -

Sequence

Protein


Download         Length: 420 a.a.        Molecular weight: 46297.48 Da        Isoelectric Point: 4.2645

>NTDB_id=317092 E1950_RS08155 WP_000472302.1 1633527..1634789(-) (clpX) [Staphylococcus aureus strain Lr12]
MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEK
AKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN
ILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNIL
TQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEE
TEPELYDAEGNLINNSKTSA

Nucleotide


Download         Length: 1263 bp        

>NTDB_id=317092 E1950_RS08155 WP_000472302.1 1633527..1634789(-) (clpX) [Staphylococcus aureus strain Lr12]
ATGTTTAAATTCAATGAAGATGAAGAAAATTTGAAATGCTCTTTCTGCGGAAAAGACCAAGATCAAGTAAAAAAACTTGT
AGCAGGAAGTGGTGTATATATTTGTAATGAGTGTATTGAATTATGCTCAGAAATCGTCGAAGAAGAATTAGCTCAAAACA
CTTCTGAAGCGATGACAGAATTACCTACTCCTAAAGAAATTATGGATCATTTAAACGAATATGTTATTGGTCAAGAAAAA
GCTAAAAAATCTTTAGCTGTAGCTGTTTATAACCACTATAAGCGTATTCAACAATTAGGACCAAAAGAAGATGATGTTGA
ATTACAAAAAAGTAACATTGCATTAATTGGGCCAACAGGTAGTGGTAAAACATTATTAGCTCAAACATTAGCCAAGACGT
TGAATGTACCATTTGCAATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTAGGCGATGATGTTGAAAATATCTTG
TTGAGATTAATTCAAGCAGCTGACTTTGACATTGATAAAGCCGAAAAAGGTATTATTTATGTAGATGAAATTGATAAAAT
TGCACGTAAATCTGAAAACACATCTATAACACGTGACGTTTCAGGTGAAGGTGTTCAACAAGCATTGCTTAAAATCTTAG
AAGGTACGACTGCAAGTGTTCCGCCACAAGGTGGACGCAAACATCCAAACCAAGAAATGATTCAAATTGATACAACAAAT
ATCTTATTTATTCTTGGTGGTGCCTTTGATGGTATTGAAGAAGTGATTAAGCGCCGTCTTGGTGAAAAAGTTATTGGTTT
CTCAAGCAATGAAGCTGATAAATATGACGAACAAGCATTATTAGCACAAATTCGCCCAGAAGATTTGCAAGCCTATGGTT
TGATTCCTGAATTTATCGGACGTGTGCCAATTGTAGCTAATTTAGAAACATTAGATGTAACTGCGTTGAAAAACATCTTA
ACGCAACCTAAAAATGCACTTGTGAAACAATATACTAAAATGCTGGAATTAGATGATGTGGATTTAGAGTTCACTGAAGA
AGCTTTATCAGCAATTAGTGAAAAAGCAATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCAATCATAGAAGAATCGT
TAATCGATATTATGTTTGATGTGCCTTCTAACGAAAATGTAACGAAGGTAGTTATTACAGCACAAACAATTAATGAAGAA
ACTGAACCAGAACTATACGACGCAGAAGGCAATTTAATTAATAATAGTAAAACATCAGCTTAA

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P63789

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

66.917

95

0.636
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.456

94.048

0.531