Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPG27_RS00210 Genome accession   NC_011333
Coordinates   37510..38253 (+) Length   247 a.a.
NCBI ID   WP_000660512.1    Uniprot ID   B5Z6A6
Organism   Helicobacter pylori G27     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32510..43253
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPG27_RS00185 (HPG27_31) panD 34668..35021 (+) 354 WP_000142221.1 aspartate 1-decarboxylase -
  HPG27_RS00190 (HPG27_32) - 35024..35326 (+) 303 WP_000347926.1 YbaB/EbfC family nucleoid-associated protein -
  HPG27_RS00195 (HPG27_33) - 35326..36321 (+) 996 WP_000468489.1 PDZ domain-containing protein -
  HPG27_RS00200 (HPG27_34) comB6 36329..37384 (+) 1056 WP_000786680.1 P-type conjugative transfer protein TrbL Machinery gene
  HPG27_RS00205 comB7 37400..37513 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  HPG27_RS00210 (HPG27_35) comB8 37510..38253 (+) 744 WP_000660512.1 virB8 family protein Machinery gene
  HPG27_RS00215 (HPG27_36) comB9 38253..39236 (+) 984 WP_012552342.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPG27_RS00220 (HPG27_37) comB10 39229..40365 (+) 1137 WP_001045858.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPG27_RS00225 (HPG27_38) - 40437..41855 (+) 1419 WP_000694877.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPG27_RS00230 (HPG27_39) gmd 41865..43010 (+) 1146 WP_000659820.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28684.91 Da        Isoelectric Point: 8.9546

>NTDB_id=31677 HPG27_RS00210 WP_000660512.1 37510..38253(+) (comB8) [Helicobacter pylori G27]
MKEKPFNSEQLIYLEELLSHQEKHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=31677 HPG27_RS00210 WP_000660512.1 37510..38253(+) (comB8) [Helicobacter pylori G27]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGATCTATTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTTCGGTTGGAAAGGAACCGCTTGAAAATCGCTT
ACAAGCTTTTAGGTTTGATGAGCTTTATCGCGCTTATCTTAGCGATCGTTTTAATCAGTGTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGCAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGTTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATTTGGAAAGAGAAGTCCATATTGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
CTCTATTGCGGCTAAACTCATGAACGAAAACAAGCTGGTGTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B5Z6A6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment