Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E5285_RS09170 Genome accession   NZ_CP038857
Coordinates   1908275..1908931 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain PigCaeca_2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1903275..1913931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5285_RS09135 (E5285_09135) dcyD 1904154..1905140 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  E5285_RS09140 (E5285_09140) tcyL 1905155..1905823 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  E5285_RS09145 (E5285_09145) tcyN 1905820..1906572 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E5285_RS09150 (E5285_09150) sdiA 1906802..1907524 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  E5285_RS09155 (E5285_09155) yecF 1907592..1907816 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  E5285_RS09160 (E5285_09160) yecU 1907803..1907979 (-) 177 WP_000590344.1 protein YecU -
  E5285_RS25025 (E5285_09165) - 1908017..1908133 (-) 117 WP_071889271.1 transcriptional regulator -
  E5285_RS09170 (E5285_09170) letA 1908275..1908931 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E5285_RS09175 (E5285_09175) uvrC 1908928..1910760 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E5285_RS09180 (E5285_09180) pgsA 1910817..1911365 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E5285_RS09200 (E5285_09200) yecA 1912015..1912680 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=316256 E5285_RS09170 WP_000611335.1 1908275..1908931(+) (letA) [Escherichia coli strain PigCaeca_2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=316256 E5285_RS09170 WP_000611335.1 1908275..1908931(+) (letA) [Escherichia coli strain PigCaeca_2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACTTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486