Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC   Type   Machinery gene
Locus tag   D4L01_RS00280 Genome accession   NZ_CP032473
Coordinates   61434..62009 (+) Length   191 a.a.
NCBI ID   WP_139541580.1    Uniprot ID   -
Organism   Helicobacter pylori strain 476-A2-EK2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 61371..74874 61434..62009 within 0


Gene organization within MGE regions


Location: 61371..74874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4L01_RS00280 comFC 61434..62009 (+) 576 WP_139541580.1 ComF family protein Machinery gene
  D4L01_RS00285 - 62042..62581 (+) 540 Protein_55 N-6 DNA methylase -
  D4L01_RS00290 - 63496..65529 (+) 2034 WP_201737473.1 relaxase/mobilization nuclease domain-containing protein -
  D4L01_RS00295 - 66683..67750 (+) 1068 WP_001120380.1 tyrosine-type recombinase/integrase -
  D4L01_RS00300 - 68064..68867 (-) 804 WP_139541581.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
  D4L01_RS00305 - 68839..69090 (-) 252 WP_127919484.1 hypothetical protein -
  D4L01_RS00310 tnpA 69385..69801 (-) 417 WP_000717709.1 IS200/IS605 family transposase -
  D4L01_RS00315 - 69838..71166 (+) 1329 WP_139541582.1 RNA-guided endonuclease TnpB family protein -
  D4L01_RS00320 - 71221..72162 (+) 942 Protein_62 N-6 DNA methylase -
  D4L01_RS00325 - 72159..73393 (+) 1235 Protein_63 restriction endonuclease subunit S -

Sequence

Protein


Download         Length: 191 a.a.        Molecular weight: 21254.74 Da        Isoelectric Point: 8.6823

>NTDB_id=316163 D4L01_RS00280 WP_139541580.1 61434..62009(+) (comFC) [Helicobacter pylori strain 476-A2-EK2]
MRCLTCLKLSFKPLCKNCLNDLPLSLRVRVLEGVSVYSFYAYSEIEELIKSKYALIGSRILPLLSQKAGAEFVKILQEQG
LNTPLYGIAIDDKIKSFYSHSAALLKGFCQGNLKPTYGTLRATNAVSYAGKSLEFRANNPRDFTFKGDENLDYFLLDDII
TTGTTLKEALKHLKALNIKAHFAIALCSADE

Nucleotide


Download         Length: 576 bp        

>NTDB_id=316163 D4L01_RS00280 WP_139541580.1 61434..62009(+) (comFC) [Helicobacter pylori strain 476-A2-EK2]
ATGCGTTGTTTAACCTGTTTGAAGCTTTCTTTCAAGCCCCTTTGCAAAAATTGCTTGAACGATCTGCCCTTAAGCTTAAG
AGTAAGGGTTTTAGAGGGCGTGAGCGTGTATAGTTTTTACGCTTATAGCGAAATAGAAGAGCTCATTAAAAGCAAATACG
CGCTGATTGGCTCTCGCATTTTGCCCTTGCTTTCTCAAAAAGCCGGCGCGGAATTTGTGAAAATCTTACAAGAACAAGGC
TTGAATACCCCCCTTTATGGCATCGCCATTGATGATAAAATCAAATCCTTTTACTCGCATTCCGCCGCGCTTTTAAAAGG
CTTTTGTCAAGGGAATTTAAAGCCCACTTATGGGACTTTAAGGGCGACTAACGCTGTTTCGTATGCCGGGAAAAGCCTGG
AATTTCGCGCCAATAACCCACGGGATTTCACTTTCAAAGGCGATGAGAATTTAGATTATTTTTTATTAGATGATATTATC
ACCACTGGCACCACCCTAAAAGAAGCCCTAAAACACCTTAAAGCTTTAAACATTAAAGCGCACTTTGCGATCGCGCTTTG
CAGCGCGGATGAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC Helicobacter pylori 26695

94.764

100

0.948
  ctsW Campylobacter jejuni subsp. jejuni 81-176

35.938

100

0.361

Multiple sequence alignment