Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLW34_RS04435 Genome accession   NZ_CP032430
Coordinates   863980..865452 (+) Length   490 a.a.
NCBI ID   WP_205288384.1    Uniprot ID   -
Organism   Lactococcus cremoris strain W34     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 858980..870452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLW34_RS04405 (LLW34_0856) - 859448..860284 (+) 837 WP_031288631.1 metallophosphoesterase -
  LLW34_RS04410 (LLW34_02870) - 860377..861288 (+) 912 Protein_851 CHAP domain-containing protein -
  LLW34_RS04415 (LLW34_02875) - 861525..861887 (+) 363 Protein_852 TIGR02328 family protein -
  LLW34_RS04420 (LLW34_0859) - 862211..862456 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLW34_RS04425 (LLW34_0860) - 862589..863119 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLW34_RS04430 (LLW34_0861) covR 863275..863967 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLW34_RS04435 (LLW34_0862) covS 863980..865452 (+) 1473 WP_205288384.1 HAMP domain-containing histidine kinase Regulator
  LLW34_RS04440 (LLW34_0863) - 865638..866879 (+) 1242 WP_205288385.1 ammonium transporter -
  LLW34_RS04445 (LLW34_0864) - 866964..867305 (+) 342 WP_205288386.1 P-II family nitrogen regulator -
  LLW34_RS04450 (LLW34_0865) murD 867474..868823 (+) 1350 WP_021211936.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLW34_RS04455 (LLW34_0866) murG 869066..870139 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55925.77 Da        Isoelectric Point: 4.7018

>NTDB_id=315814 LLW34_RS04435 WP_205288384.1 863980..865452(+) (covS) [Lactococcus cremoris strain W34]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGFG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=315814 LLW34_RS04435 WP_205288384.1 863980..865452(+) (covS) [Lactococcus cremoris strain W34]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACGTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGTTTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.694

100

0.947

Multiple sequence alignment