Detailed information NTG0315186

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: D4A37_RS06020
• Genome accession: NZ_CP032365
• Coordinates: 1158270..1160870 (+)
• Length: 866 a.a.
• NCBI ID: WP_000365386.1
• Uniprot ID: A0A1G6Y7S4
• Organism: Bacillus wiedmannii strain SR52
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1153270..1165870

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D4A37_RS05985	prsA	1154044..1154901 (-)	858	WP_151035331.1	peptidylprolyl isomerase PrsA	-
D4A37_RS05990	-	1155032..1155163 (-)	132	WP_001120852.1	DUF3941 domain-containing protein	-
D4A37_RS05995	-	1155264..1156121 (+)	858	WP_000364451.1	YitT family protein	-
D4A37_RS06000	-	1156147..1156344 (-)	198	WP_000527398.1	DUF3813 domain-containing protein	-
D4A37_RS06005	-	1156345..1156485 (-)	141	WP_000516816.1	hypothetical protein	-
D4A37_RS06010	-	1156590..1157399 (-)	810	WP_001041224.1	Cof-type HAD-IIB family hydrolase	-
D4A37_RS06015	-	1157892..1158071 (+)	180	WP_000531420.1	YjzC family protein	-
D4A37_RS06020	clpC	1158270..1160870 (+)	2601	WP_000365386.1	ATP-dependent chaperone ClpB	Regulator
D4A37_RS06025	-	1160907..1161089 (-)	183	WP_001211110.1	YjzD family protein	-
D4A37_RS06030	-	1161246..1161980 (+)	735	WP_000028707.1	hydrolase	-
D4A37_RS06035	-	1162010..1162882 (+)	873	WP_141545409.1	NAD(P)-dependent oxidoreductase	-
D4A37_RS06040	comZ	1162936..1163112 (+)	177	WP_001003337.1	ComZ family protein	Regulator
D4A37_RS06045	fabH	1163344..1164276 (+)	933	WP_097918337.1	beta-ketoacyl-ACP synthase III	-
D4A37_RS06050	fabF	1164308..1165546 (+)	1239	WP_000412646.1	beta-ketoacyl-ACP synthase II	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97402.47 Da
• Isoelectric Point: 5.2357

>NTDB_id=315186 D4A37_RS06020 WP_000365386.1 1158270..1160870(+) (clpC) [Bacillus wiedmannii strain SR52]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVESLIKKKPSVTGSGAE
VGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINQLLTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLGADGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAREFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=315186 D4A37_RS06020 WP_000365386.1 1158270..1160870(+) (clpC) [Bacillus wiedmannii strain SR52]
ATGGACTTAAATCAAATGACAACAAAAACGCAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCATCA
AGAAGTAGATACTGTTCATCTCTTGTTTACATTATTAGAAGAGCAAGATGGGTTAGCAGTGCGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCGTTAAAGCAAGGCGTCGAAAGTTTAATTAAGAAAAAACCTTCTGTAACGGGAAGCGGTGCAGAA
GTAGGAAAATTATATATAACAGGTGCTCTGCAACAACTACTTGTAAGAGCAGGAAAAGAAGCAGAGAAATTGCAAGATGA
CTACATTTCAGTTGAACATGTATTGCTTGCTTTTTCAGAAGAAAAAGGCGATATAAATCAATTACTTACAAGATTTCACA
TTACAAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATTGATCCTGTTATCGGTCGCGA
TAGTGAAATTCGACGTGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCGGTTTTAATTGGTGAACCCGGTGTTG
GTAAAACAGCAATCGTTGAAGGATTAGCACAGCGTATTGTGAAGAAGGATGTACCAGAAGGATTAAAAGATAGAACAATC
TTCGCATTAGATATGAGTGCGCTTGTAGCTGGAGCGAAATTCCGTGGTGAGTTTGAAGAGCGTCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGCATTTTATTATTCATTGATGAACTTCACACAATCGTCGGCGCTGGTAAAACAGAAG
GTGCGATGGACGCAGGAAATATGTTAAAACCGATGCTTGCGCGTGGTGAACTGCATTGTATCGGGGCGACAACGTTAGAT
GAGTATCGTAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGCTTTGAAATTTATCATGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCCGTTTTATCAGATCGATATATTTCGGATCGTTTCTTACCAGATAAAGCGATTGATCTTGTTGACGAAGCG
TGCGCAACGATTCGAACAGAGATTGATTCTATGCCGACAGAATTAGATGAAGTAACGCGCCGCATTATGCAGCTGGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGCCTGAAAACGTTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCGAAATGGGAGAAAGAAAAAGAAGACATTCATAAAGTGCGTGACTTACGTGAA
CATTTAGAGCGCTTGCGCCGTGAGTTAGAAGAAGCAGAAGGAAATTACGATTTAAATAAAGCAGCTGAACTTCGTCACGG
GAAAATTCCAGCTATCGAAAAAGAGTTAAAAGAAGCGGAAGAAATGGGTGCACATAATAAACAAGAGAATCGCTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATTGCTGATATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGCGAGAAATTACTACGGTTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGCTTAGTATC
AGACGCAGTTCTTCGTGCACGCGCTGGTATTAAAGACCCGAACCGTCCAATTGGTTCCTTCATCTTTTTAGGACCGACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCACAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGTATCGACATG
TCTGAGTATATGGAGAAACACGCTGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGGTATGAAGAGGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCGTATTCAGTTATTTTGTTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCTCAAGGACGTACAGTAGACTTTAAAAACACGGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTGTTAGATGGATTAGGAGCAGATGGCTCAATTAAAGAGGAATCAAGAGA
ACTTGTAATGGGGCAATTAAGAGGACATTTCCGACCAGAGTTTTTAAACCGTGTCGATGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGGCGTTTAGCTGACCGTCATATTACA
GTAGAATTAACAGACGCAGCGAGAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG
ATATGTACAGCGTCAAGTTGAGACGAAATTAGCGAGAGAATTAATTGCAGGAACAATTACTGATAACAGTCACGTAGTTG
TTGATGTGGAAAATAACGAATTAGTCGTTCATGTAAAGTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA lid domain (AAA_lid_9) (345-447)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

3D structure

• AlphaFold DB: A0A1G6Y7S4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	47.125	82.333	0.388