Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SEZ_RS07525 Genome accession   NC_011134
Coordinates   1595081..1596403 (-) Length   440 a.a.
NCBI ID   WP_012516136.1    Uniprot ID   B4U4G3
Organism   Streptococcus equi subsp. zooepidemicus MGCS10565     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1590081..1601403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEZ_RS07515 (Sez_1545) raiA 1593817..1594365 (-) 549 WP_012516134.1 ribosome-associated translation inhibitor RaiA -
  SEZ_RS07520 (Sez_1546) - 1594441..1595022 (-) 582 WP_012516135.1 ComF family protein -
  SEZ_RS07525 (Sez_1547) comFA/cflA 1595081..1596403 (-) 1323 WP_012516136.1 DEAD/DEAH box helicase Machinery gene
  SEZ_RS07530 (Sez_1548) - 1596459..1597100 (+) 642 WP_012516137.1 YigZ family protein -
  SEZ_RS07535 (Sez_1549) cysK 1597222..1598148 (+) 927 WP_012516138.1 cysteine synthase A -
  SEZ_RS07540 (Sez_1551) - 1598535..1598897 (-) 363 WP_012516140.1 S1 RNA-binding domain-containing protein -
  SEZ_RS07545 (Sez_1552) - 1598897..1600297 (-) 1401 WP_021321065.1 Cof-type HAD-IIB family hydrolase -
  SEZ_RS07550 (Sez_1553) - 1600331..1600972 (-) 642 WP_041785672.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 49868.96 Da        Isoelectric Point: 9.6948

>NTDB_id=31386 SEZ_RS07525 WP_012516136.1 1595081..1596403(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MENIENYYGRLFPEGKCPKAVSAWACSLQSMIAKKGTLYCQRCGSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
ASFPKGHYLRWQGQLTTYQAAVSHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVNKGGWVCIASPRVDVCIELEKR
LSRDFSCQVCLMHAESEVYHRSPIIVATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKADAVTVYLTATST
RDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLEAINRGKLPRRFITLVKKQRATGYPLLIFFPIIELAEQCCQL
LQKYFPKETIAHASSQSSNRMAIIEQFRQGQITILISTTILERGVTFPTVDVFVLLANHRLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISQAMLKAVREIKDMNQKGYQNELSTLPQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=31386 SEZ_RS07525 WP_012516136.1 1595081..1596403(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGGAGAATATCGAAAATTACTATGGACGCCTTTTCCCTGAAGGGAAATGCCCAAAGGCTGTTTCTGCCTGGGCTTGCAG
CTTACAAAGCATGATCGCTAAAAAAGGAACGTTATACTGCCAACGCTGTGGCAGTTTAATTGAGAAGGCTCATCAGCTGC
CTAGCGGTGCTTACTACTGTAGAGCCTGTCTTGTTTTTGGTCGAAACCAATCTGATCGCCCCTTGCTCTATTTTCCACCG
GCTTCTTTTCCAAAGGGACATTATCTGAGGTGGCAAGGACAGCTCACGACATATCAGGCAGCTGTCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACCTTAGTTCATGCGGTTACTGGTGCTGGCAAAACAGAGATGATGTATGAAGCTA
TTGCAGCAGTTGTTAATAAGGGTGGCTGGGTCTGCATTGCTAGTCCACGAGTTGATGTCTGCATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAGTCTGCCTTATGCATGCTGAGTCAGAGGTTTATCATAGAAGTCCCATTATCGTTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTTCCCTTTGTCA
ATAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAGCAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AGAGATTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACGTTGGCAAGAAGATTCCATGGCAAGCCTTTAGT
TGTTCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGGCTATCAATCGCGGGAAATTGCCTAGAAGGTTCATCACCCTAG
TCAAAAAACAAAGGGCAACCGGCTATCCTCTTTTAATCTTTTTTCCGATTATTGAGCTGGCTGAGCAATGCTGTCAGCTG
TTACAAAAGTATTTTCCTAAGGAAACTATTGCTCATGCTTCCAGTCAGTCATCAAATCGAATGGCTATCATTGAGCAATT
CAGACAAGGACAAATCACTATACTTATATCAACAACCATTTTGGAAAGAGGTGTGACTTTTCCAACCGTAGATGTCTTTG
TCTTATTAGCCAATCATCGCCTTTACACAAGCAGCAGTCTTATTCAAATTTCAGGTCGCGTTGGGCGCTCTTTGGAAAGA
CCTGAAGGACAGGTGCTATTTTTTCATGATGGTATTAGCCAGGCTATGCTCAAGGCAGTGCGGGAGATAAAGGACATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGCCACAATAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-396)

DEAD/DEAH box helicase (DEAD)

(98-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U4G3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae D39

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae R6

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae Rx1

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae TIGR4

53.176

96.591

0.514
  comFA/cflA Streptococcus mitis NCTC 12261

52.941

96.591

0.511
  comFA Lactococcus lactis subsp. cremoris KW2

48.214

89.091

0.43

Multiple sequence alignment