Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E3157_RS10165 Genome accession   NZ_CP038386
Coordinates   2125331..2125987 (+) Length   218 a.a.
NCBI ID   WP_000611325.1    Uniprot ID   -
Organism   Escherichia coli O55:H7 strain DEC5D     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2120331..2130987
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3157_RS10135 (E3157_10380) dcyD 2121210..2122196 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  E3157_RS10140 (E3157_10385) tcyL 2122211..2122879 (+) 669 WP_001158226.1 cystine ABC transporter permease -
  E3157_RS10145 (E3157_10390) tcyN 2122876..2123628 (+) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E3157_RS10150 (E3157_10395) sdiA 2123858..2124580 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  E3157_RS10155 (E3157_10400) yecF 2124648..2124872 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  E3157_RS10160 (E3157_10405) yecU 2124859..2125035 (-) 177 WP_001302050.1 protein YecU -
  E3157_RS26045 (E3157_10410) - 2125073..2125189 (-) 117 WP_001302039.1 hypothetical protein -
  E3157_RS10165 (E3157_10415) letA 2125331..2125987 (+) 657 WP_000611325.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E3157_RS10170 (E3157_10420) uvrC 2125984..2127816 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E3157_RS10175 (E3157_10425) pgsA 2127873..2128421 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E3157_RS10195 (E3157_10445) yecA 2129070..2129735 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23844.59 Da        Isoelectric Point: 6.9614

>NTDB_id=313703 E3157_RS10165 WP_000611325.1 2125331..2125987(+) (letA) [Escherichia coli O55:H7 strain DEC5D]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSIPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=313703 E3157_RS10165 WP_000611325.1 2125331..2125987(+) (letA) [Escherichia coli O55:H7 strain DEC5D]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATACCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.242

94.954

0.477
  letA Legionella pneumophila strain ERS1305867

50.242

94.954

0.477