Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E3158_RS15775 Genome accession   NZ_CP038383
Coordinates   3194096..3194752 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O55:H7 strain DEC5E     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3189096..3199752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3158_RS15735 (E3158_16140) - 3189608..3189868 (+) 261 WP_000488112.1 ogr/Delta-like zinc finger family protein -
  E3158_RS15740 (E3158_16145) - 3190060..3190200 (+) 141 WP_000078920.1 Hok/Gef family protein -
  E3158_RS15745 (E3158_16150) - 3190389..3190670 (-) 282 WP_001303543.1 hypothetical protein -
  E3158_RS15765 (E3158_16170) pgsA 3191662..3192210 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E3158_RS15770 (E3158_16175) uvrC 3192267..3194099 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E3158_RS15775 (E3158_16180) letA 3194096..3194752 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E3158_RS29015 (E3158_16185) - 3194894..3195010 (+) 117 WP_001302039.1 hypothetical protein -
  E3158_RS15780 (E3158_16190) yecU 3195048..3195224 (+) 177 WP_001302050.1 protein YecU -
  E3158_RS15785 (E3158_16195) yecF 3195211..3195435 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  E3158_RS15790 (E3158_16200) sdiA 3195503..3196225 (-) 723 WP_001154288.1 transcriptional regulator SdiA -
  E3158_RS15795 (E3158_16205) tcyN 3196455..3197207 (-) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E3158_RS15800 (E3158_16210) tcyL 3197204..3197872 (-) 669 WP_001158226.1 cystine ABC transporter permease -
  E3158_RS15805 (E3158_16215) dcyD 3197887..3198873 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=313629 E3158_RS15775 WP_000611328.1 3194096..3194752(-) (letA) [Escherichia coli O55:H7 strain DEC5E]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=313629 E3158_RS15775 WP_000611328.1 3194096..3194752(-) (letA) [Escherichia coli O55:H7 strain DEC5E]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482