Detailed information
Bioinformatically predicted
Overview
| Name | pilA | Type | Machinery gene |
| Locus tag | D1112_RS04405 | Genome accession | NZ_CP031854 |
| Coordinates | 989298..989744 (-) | Length | 148 a.a. |
| NCBI ID | WP_005597397.1 | Uniprot ID | B0BPG5 |
| Organism | Actinobacillus pleuropneumoniae strain ORG1224 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 984298..994744
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D1112_RS04380 (D1112_04400) | yacG | 985205..985393 (-) | 189 | WP_005597388.1 | DNA gyrase inhibitor YacG | - |
| D1112_RS04385 (D1112_04405) | coaE | 985375..986013 (-) | 639 | WP_005601202.1 | dephospho-CoA kinase | - |
| D1112_RS04390 (D1112_04410) | - | 986035..986673 (-) | 639 | WP_005604550.1 | prepilin peptidase | - |
| D1112_RS04395 (D1112_04415) | pilC | 986700..987902 (-) | 1203 | WP_012263006.1 | type II secretion system F family protein | Machinery gene |
| D1112_RS04400 (D1112_04420) | pilB | 987886..989280 (-) | 1395 | WP_005601209.1 | GspE/PulE family protein | Machinery gene |
| D1112_RS04405 (D1112_04425) | pilA | 989298..989744 (-) | 447 | WP_005597397.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | Machinery gene |
| D1112_RS04410 (D1112_04430) | radA | 989926..991305 (+) | 1380 | WP_237601081.1 | DNA repair protein RadA | - |
| D1112_RS04415 (D1112_04435) | - | 991349..991582 (-) | 234 | WP_005597399.1 | YgjV family protein | - |
| D1112_RS04420 (D1112_04440) | folA | 991709..992197 (-) | 489 | WP_012263007.1 | type 3 dihydrofolate reductase | - |
| D1112_RS04425 (D1112_04445) | proB | 992284..993375 (+) | 1092 | WP_237586572.1 | glutamate 5-kinase | - |
| D1112_RS04430 (D1112_04450) | - | 993388..994164 (+) | 777 | WP_237586573.1 | TSUP family transporter | - |
Sequence
Protein
Download Length: 148 a.a. Molecular weight: 15980.38 Da Isoelectric Point: 7.6257
>NTDB_id=311893 D1112_RS04405 WP_005597397.1 989298..989744(-) (pilA) [Actinobacillus pleuropneumoniae strain ORG1224]
MQKLSLIRPLTNAFTLIELMIVIAIIAILATVAIPSYNSYTQKAALSELLAASASYKTDVEICIYNTGDSKNCSGGQNGV
RKMTELRQAKYLNAITVEGGTITVTGKGNLQEYGYTMTPIHNGSTISWETKCKGEDLSLFPANFCASN
MQKLSLIRPLTNAFTLIELMIVIAIIAILATVAIPSYNSYTQKAALSELLAASASYKTDVEICIYNTGDSKNCSGGQNGV
RKMTELRQAKYLNAITVEGGTITVTGKGNLQEYGYTMTPIHNGSTISWETKCKGEDLSLFPANFCASN
Nucleotide
Download Length: 447 bp
>NTDB_id=311893 D1112_RS04405 WP_005597397.1 989298..989744(-) (pilA) [Actinobacillus pleuropneumoniae strain ORG1224]
ATGCAAAAACTAAGTCTTATTCGACCGCTTACTAACGCGTTTACTTTAATTGAATTGATGATCGTGATTGCGATTATTGC
CATTTTAGCTACGGTTGCAATTCCGTCATATAACAGTTATACCCAAAAAGCGGCGCTTTCGGAGCTATTGGCGGCATCGG
CTTCTTATAAAACGGATGTCGAGATCTGCATATATAACACCGGAGATTCTAAAAACTGTAGCGGCGGTCAAAACGGTGTC
AGAAAAATGACGGAGCTTAGACAGGCTAAATATTTAAATGCCATTACGGTGGAAGGCGGAACGATTACGGTAACGGGGAA
GGGGAATCTGCAGGAATACGGTTATACGATGACACCGATTCATAACGGTAGCACTATTTCTTGGGAAACGAAATGTAAAG
GGGAGGACTTAAGTTTATTTCCGGCAAATTTCTGCGCATCAAATTAA
ATGCAAAAACTAAGTCTTATTCGACCGCTTACTAACGCGTTTACTTTAATTGAATTGATGATCGTGATTGCGATTATTGC
CATTTTAGCTACGGTTGCAATTCCGTCATATAACAGTTATACCCAAAAAGCGGCGCTTTCGGAGCTATTGGCGGCATCGG
CTTCTTATAAAACGGATGTCGAGATCTGCATATATAACACCGGAGATTCTAAAAACTGTAGCGGCGGTCAAAACGGTGTC
AGAAAAATGACGGAGCTTAGACAGGCTAAATATTTAAATGCCATTACGGTGGAAGGCGGAACGATTACGGTAACGGGGAA
GGGGAATCTGCAGGAATACGGTTATACGATGACACCGATTCATAACGGTAGCACTATTTCTTGGGAAACGAAATGTAAAG
GGGAGGACTTAAGTTTATTTCCGGCAAATTTCTGCGCATCAAATTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilA | Glaesserella parasuis strain SC1401 |
68.919 |
100 |
0.689 |
| pilA | Haemophilus influenzae 86-028NP |
55.102 |
99.324 |
0.547 |
| pilA | Haemophilus influenzae Rd KW20 |
53.061 |
99.324 |
0.527 |