Detailed information NTG0311688

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: D1G35_RS06250
• Genome accession: NZ_CP031838
• Coordinates: 1171746..1172432 (+)
• Length: 228 a.a.
• NCBI ID: WP_072361794.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain QD-CD9
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1166746..1177432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1G35_RS06205 (D1G35_06205)	yqeH	1166747..1167847 (+)	1101	WP_001280141.1	ribosome biogenesis GTPase YqeH	-
D1G35_RS06210 (D1G35_06210)	-	1167877..1168110 (+)	234	Protein_1125	ribosome biogenesis GTPase YqeH	-
D1G35_RS06215 (D1G35_06215)	-	1168140..1168373 (+)	234	Protein_1126	ribosome biogenesis GTPase YqeH	-
D1G35_RS06220 (D1G35_06220)	aroE	1168387..1169193 (+)	807	WP_000666761.1	shikimate dehydrogenase	-
D1G35_RS06225 (D1G35_06225)	yhbY	1169197..1169487 (+)	291	WP_000627815.1	ribosome assembly RNA-binding protein YhbY	-
D1G35_RS06230 (D1G35_06230)	nadD	1169490..1170059 (+)	570	WP_000725162.1	nicotinate (nicotinamide) nucleotide adenylyltransferase	-
D1G35_RS06235 (D1G35_06235)	yqeK	1170049..1170633 (+)	585	WP_001019326.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
D1G35_RS06240 (D1G35_06240)	rsfS	1170634..1170987 (+)	354	WP_001088020.1	ribosome silencing factor	-
D1G35_RS06245 (D1G35_06245)	-	1170990..1171706 (+)	717	WP_000084822.1	class I SAM-dependent methyltransferase	-
D1G35_RS06250 (D1G35_06250)	comEA	1171746..1172432 (+)	687	WP_072361794.1	ComEA family DNA-binding protein	Machinery gene
D1G35_RS06255 (D1G35_06255)	-	1172524..1172985 (+)	462	WP_000439693.1	ComE operon protein 2	-
D1G35_RS06260 (D1G35_06260)	comEC	1172990..1175191 (+)	2202	WP_025174327.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
D1G35_RS06265 (D1G35_06265)	holA	1175248..1176222 (+)	975	WP_031587652.1	DNA polymerase III subunit delta	-
D1G35_RS06270 (D1G35_06270)	rpsT	1176267..1176518 (-)	252	WP_001274017.1	30S ribosomal protein S20	-

Sequence

Protein

• Length: 228 a.a.
• Molecular weight: 25863.49 Da
• Isoelectric Point: 9.3305

>NTDB_id=311688 D1G35_RS06250 WP_072361794.1 1171746..1172432(+) (comEA) [Staphylococcus aureus strain QD-CD9]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide

• Length: 687 bp

>NTDB_id=311688 D1G35_RS06250 WP_072361794.1 1171746..1172432(+) (comEA) [Staphylococcus aureus strain QD-CD9]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (164-227)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Staphylococcus aureus MW2	98.678	99.561	0.982
comEA	Staphylococcus aureus N315	97.797	99.561	0.974