Detailed information NTG0031046

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SSU_RS09600
• Genome accession: NC_012925
• Coordinates: 1939092..1941632 (-)
• Length: 846 a.a.
• NCBI ID: WP_012775399.1
• Uniprot ID: A0A0H3MXU9
• Organism: Streptococcus suis P1/7
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1934092..1946632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU_RS09580 (SSU1904)	-	1936454..1937743 (+)	1290	WP_012775456.1	IS4 family transposase	-
SSU_RS09585 (SSU1905)	-	1937858..1938046 (-)	189	WP_014636177.1	hypothetical protein	-
SSU_RS09590 (SSU1906)	-	1938080..1938520 (-)	441	WP_012027998.1	DUF3021 domain-containing protein	-
SSU_RS09595 (SSU1907)	-	1938517..1938960 (-)	444	WP_012027999.1	LytTR family DNA-binding domain-containing protein	-
SSU_RS09600 (SSU1908)	hexA	1939092..1941632 (-)	2541	WP_012775399.1	DNA mismatch repair protein MutS	Machinery gene
SSU_RS09605 (SSU1909)	argR	1941647..1942087 (-)	441	WP_002937036.1	arginine repressor	-
SSU_RS09610 (SSU1910)	argS	1942194..1943882 (+)	1689	WP_012028003.1	arginine--tRNA ligase	-
SSU_RS09615 (SSU1911)	-	1944062..1944976 (+)	915	WP_012775400.1	SH3 domain-containing protein	-
SSU_RS09620 (SSU1912)	-	1945029..1945550 (-)	522	WP_012775401.1	ABC transporter permease	-
SSU_RS09625 (SSU1913)	-	1945662..1945844 (+)	183	WP_002937045.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95116.55 Da
• Isoelectric Point: 4.8252

>NTDB_id=31046 SSU_RS09600 WP_012775399.1 1939092..1941632(-) (hexA) [Streptococcus suis P1/7]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTHPAPSVV
EEPSGQLDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=31046 SSU_RS09600 WP_012775399.1 1939092..1941632(-) (hexA) [Streptococcus suis P1/7]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAAAATCCGATTCCCATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTACAGTTCGCGCTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAGATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGCTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGTTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATTTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTAGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCATCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTTACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATTGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACACATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGAC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCATGACAAGATTGGTGCCAAGACTCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCAGATCGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAACTCACCCAGCTCCGTCAGTAGTG
GAAGAACCGTCAGGTCAACTTGATCTCTTCGCAGACACGCCTTCTCACCCAGTACTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCTATGGAAGTCATGATGGCGGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

3D structure

• AlphaFold DB: A0A0H3MXU9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.877	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	37.762	100	0.383