Detailed information NTG0310288

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: DXY22_RS00340
• Genome accession: NZ_CP031693
• Coordinates: 64092..65249 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: A0A199WDV9
• Organism: Bacillus subtilis strain SRCM101393
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 59092..70249

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DXY22_RS00310 (DXY22_00061)	yvyF	59345..59764 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
DXY22_RS00315 (DXY22_00062)	comFC	59838..60560 (-)	723	WP_003227991.1	comF operon protein ComFC	Machinery gene
DXY22_RS00320 (DXY22_00063)	comFB	60524..60820 (-)	297	WP_003227989.1	late competence protein ComFB	-
DXY22_RS00325 (DXY22_00064)	comFA	60880..62271 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
DXY22_RS00330 (DXY22_00065)	fakBA	62377..63222 (-)	846	WP_003244125.1	DegV family protein	-
DXY22_RS00335 (DXY22_00066)	degU	63320..64009 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
DXY22_RS00340 (DXY22_00067)	degS	64092..65249 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
DXY22_RS00345 (DXY22_00068)	yvyE	65466..66119 (+)	654	WP_003227979.1	YigZ family protein	-
DXY22_RS00350 (DXY22_00069)	tagV	66119..67294 (+)	1176	WP_015251114.1	polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagV	-
DXY22_RS00355 (DXY22_00070)	tagO	67368..68444 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
DXY22_RS00360 (DXY22_00071)	tuaH	68589..69782 (-)	1194	WP_015251113.1	glycosyltransferase family 1 protein	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=310288 DXY22_RS00340 WP_003227983.1 64092..65249(-) (degS) [Bacillus subtilis strain SRCM101393]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=310288 DXY22_RS00340 WP_003227983.1 64092..65249(-) (degS) [Bacillus subtilis strain SRCM101393]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACTCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATCATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTACGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: A0A199WDV9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1