Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ES276_RS09150 Genome accession   NZ_CP038252
Coordinates   1808733..1809365 (-) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1803733..1814365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS09120 (ES276_09695) - 1804164..1805504 (+) 1341 Protein_1799 IS3 family transposase -
  ES276_RS09125 (ES276_09700) cbpF 1805632..1806654 (-) 1023 WP_000771060.1 choline-binding protein CbpF -
  ES276_RS09130 (ES276_09705) cbpG 1806673..1807494 (-) 822 WP_001100143.1 choline-binding protein CbpG -
  ES276_RS09135 (ES276_09710) - 1807575..1807814 (-) 240 WP_000754501.1 hypothetical protein -
  ES276_RS09140 - 1807964..1808732 (-) 769 Protein_1803 DNA alkylation repair protein -
  ES276_RS09150 (ES276_09730) vraR 1808733..1809365 (-) 633 WP_000698434.1 response regulator transcription factor Regulator
  ES276_RS09155 (ES276_09735) - 1809379..1810374 (-) 996 WP_000743672.1 sensor histidine kinase -
  ES276_RS09160 (ES276_09740) liaF 1810371..1811069 (-) 699 WP_001224636.1 cell wall-active antibiotics response protein LiaF -
  ES276_RS09165 (ES276_09745) fni 1811146..1812156 (-) 1011 WP_000210618.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  ES276_RS09170 (ES276_09750) - 1812140..1813147 (-) 1008 WP_000562415.1 phosphomevalonate kinase -
  ES276_RS09175 (ES276_09755) mvaD 1813134..1814087 (-) 954 WP_000373458.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=310262 ES276_RS09150 WP_000698434.1 1808733..1809365(-) (vraR) [Streptococcus pneumoniae strain TVO_1901936]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=310262 ES276_RS09150 WP_000698434.1 1808733..1809365(-) (vraR) [Streptococcus pneumoniae strain TVO_1901936]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41