Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ES276_RS03455 Genome accession   NZ_CP038252
Coordinates   659785..660462 (+) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 654785..665462
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS03425 (ES276_03630) - 655127..655676 (-) 550 Protein_649 nicotinamide mononucleotide transporter -
  ES276_RS03430 (ES276_03640) - 655978..656628 (-) 651 WP_000188498.1 metal-dependent transcriptional regulator -
  ES276_RS03435 (ES276_03645) - 656740..657582 (+) 843 WP_000160958.1 metallophosphoesterase -
  ES276_RS03440 (ES276_03650) - 657658..658095 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  ES276_RS03445 (ES276_03655) - 658163..658465 (+) 303 WP_000281594.1 hypothetical protein -
  ES276_RS03450 (ES276_03660) - 658556..659629 (-) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  ES276_RS03455 (ES276_03665) braR 659785..660462 (+) 678 WP_000548959.1 response regulator transcription factor Regulator
  ES276_RS03460 (ES276_03670) - 660455..661429 (+) 975 WP_000887948.1 HAMP domain-containing histidine kinase -
  ES276_RS03465 (ES276_03675) thrS 661478..663421 (-) 1944 WP_000608361.1 threonine--tRNA ligase -
  ES276_RS03470 (ES276_03680) - 663479..663802 (-) 324 WP_000422779.1 MazG-like protein -
  ES276_RS10895 - 664059..664433 (-) 375 Protein_659 hypothetical protein -
  ES276_RS03475 (ES276_03700) - 664669..665298 (+) 630 WP_000762092.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=310214 ES276_RS03455 WP_000548959.1 659785..660462(+) (braR) [Streptococcus pneumoniae strain TVO_1901936]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=310214 ES276_RS03455 WP_000548959.1 659785..660462(+) (braR) [Streptococcus pneumoniae strain TVO_1901936]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment