Detailed information NTG0310144

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ES300_RS09140
• Genome accession: NZ_CP038251
• Coordinates: 1801567..1802466 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904834.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901944
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1796567..1807466

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES300_RS09115 (ES300_09615)	rsmA	1796804..1797676 (-)	873	WP_001216878.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
ES300_RS10905	-	1798062..1798208 (-)	147	WP_000333269.1	hypothetical protein	-
ES300_RS09125 (ES300_09620)	-	1798201..1798842 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
ES300_RS09130 (ES300_09625)	-	1798844..1800874 (-)	2031	WP_000825268.1	bacteriocin-associated integral membrane family protein	-
ES300_RS09135 (ES300_09630)	-	1800951..1801247 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
ES300_RS09140 (ES300_09635)	comR	1801567..1802466 (-)	900	WP_000904834.1	helix-turn-helix transcriptional regulator	Regulator
ES300_RS09145 (ES300_09640)	rnmV	1802538..1803098 (-)	561	WP_000664448.1	ribonuclease M5	-
ES300_RS09150 (ES300_09645)	-	1803098..1803871 (-)	774	WP_000575594.1	TatD family hydrolase	-
ES300_RS09155 (ES300_09655)	-	1804176..1805147 (-)	972	Protein_1820	DUF1542 domain-containing protein	-
ES300_RS09160 (ES300_09665)	rpmH	1805353..1805487 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
ES300_RS09165 (ES300_09670)	-	1805632..1806846 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
ES300_RS09170 (ES300_09675)	-	1807002..1807295 (-)	294	WP_000977374.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35263.10 Da
• Isoelectric Point: 4.9762

>NTDB_id=310144 ES300_RS09140 WP_000904834.1 1801567..1802466(-) (comR) [Streptococcus pneumoniae strain TVO_1901944]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=310144 ES300_RS09140 WP_000904834.1 1801567..1802466(-) (comR) [Streptococcus pneumoniae strain TVO_1901944]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	38.144	97.324	0.371
comR	Streptococcus suis 05ZYH33	38.144	97.324	0.371
comR	Streptococcus suis D9	36.12	100	0.361