Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ES300_RS07355 Genome accession   NZ_CP038251
Coordinates   1465763..1466440 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain TVO_1901944     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1460763..1471440
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES300_RS07330 (ES300_07700) - 1460928..1461558 (-) 631 Protein_1476 NAD(P)-dependent oxidoreductase -
  ES300_RS07335 - 1461799..1462166 (+) 368 Protein_1477 hypothetical protein -
  ES300_RS07340 (ES300_07720) - 1462423..1462746 (+) 324 WP_000422771.1 hypothetical protein -
  ES300_RS07345 (ES300_07725) thrS 1462804..1464747 (+) 1944 WP_000608333.1 threonine--tRNA ligase -
  ES300_RS07350 (ES300_07730) - 1464796..1465770 (-) 975 WP_000887947.1 HAMP domain-containing histidine kinase -
  ES300_RS07355 (ES300_07735) braR 1465763..1466440 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  ES300_RS07360 (ES300_07740) - 1466596..1467669 (+) 1074 WP_001273825.1 DUF2974 domain-containing protein -
  ES300_RS07365 (ES300_07745) - 1467760..1468062 (-) 303 WP_000281595.1 hypothetical protein -
  ES300_RS07370 (ES300_07750) - 1468131..1468568 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  ES300_RS07375 (ES300_07755) - 1468644..1469486 (-) 843 WP_000160935.1 metallophosphoesterase -
  ES300_RS07380 (ES300_07760) - 1469598..1470248 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  ES300_RS07385 (ES300_07770) - 1470436..1471101 (+) 666 WP_029645487.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=310122 ES300_RS07355 WP_000548959.1 1465763..1466440(-) (braR) [Streptococcus pneumoniae strain TVO_1901944]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=310122 ES300_RS07355 WP_000548959.1 1465763..1466440(-) (braR) [Streptococcus pneumoniae strain TVO_1901944]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment