Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ES300_RS02835 Genome accession   NZ_CP038251
Coordinates   563193..565037 (+) Length   614 a.a.
NCBI ID   WP_001061110.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901944     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 558193..570037
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES300_RS02815 (ES300_02970) - 559026..559805 (+) 780 WP_000290025.1 alpha/beta hydrolase family protein -
  ES300_RS02820 (ES300_02975) murM 559917..561137 (+) 1221 WP_000286563.1 peptidoglycan bridge formation alanyltransferase MurM -
  ES300_RS02825 (ES300_02980) murN 561142..562374 (+) 1233 WP_001229506.1 peptidoglycan bridge formation alanyltransferase MurN -
  ES300_RS02830 (ES300_02985) - 562453..563154 (+) 702 WP_001267412.1 M57 family metalloprotease -
  ES300_RS02835 (ES300_02990) uvrC 563193..565037 (+) 1845 WP_001061110.1 excinuclease ABC subunit UvrC Machinery gene
  ES300_RS02840 (ES300_02995) - 565027..565860 (+) 834 WP_001015794.1 metallophosphoesterase -
  ES300_RS02845 (ES300_03000) - 566038..566838 (-) 801 WP_000714618.1 amino acid ABC transporter substrate-binding protein -
  ES300_RS02850 (ES300_03005) - 567009..567614 (+) 606 WP_000670149.1 nitroreductase family protein -
  ES300_RS02855 (ES300_03010) pepV 567627..569027 (+) 1401 WP_000560278.1 dipeptidase PepV -
  ES300_RS02860 (ES300_03015) - 569081..569659 (+) 579 WP_000078158.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70483.97 Da        Isoelectric Point: 8.8656

>NTDB_id=310085 ES300_RS02835 WP_001061110.1 563193..565037(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901944]
MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDTKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSL
TKIKEASVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=310085 ES300_RS02835 WP_001061110.1 563193..565037(+) (uvrC) [Streptococcus pneumoniae strain TVO_1901944]
ATGAACAACTTGATTAAACCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTTACAAGGATAAAAACGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGCGTGAGGTCTTATTTCCGTGGAAGTCATGATACCAAAACAG
AGGCCTTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCGCTTCTGCTGGAAATCAAC
CTGATCAAGGAAAATAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCTTATCCTTTTATCAAAATCACCAATGA
GCACTATCCACGGCTTATCATTACTCGTCAGGTCAAAAAGGACGGTGGTCTTTATTTTGGCCCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTTCTAGATAGGATTTTCCCTTTTCGAAAATGTACCAACCCGCCCTCTAAGGTCTGTTTT
TACTACCATATCGGCCAATGTATGGCCCACACCATCTGTAAGAATGACGAGGCCTATTTCAAGTCCATGGCCCAGGAGGT
GTCTGATTTTCTGAAAGGTCAGGATGACAAAATCATCGATGATCTCAAGAGTAAAATGGCAGTAACAGCACAAAGTATGG
AGTTTGAACGGGCAGCGGAATACCGTGACCTGATTCAGGCCATTGGAACACTTCGAACCAAGCAACGGGTCATGGCTAAG
GATCTCCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTTCGTCAGGG
CAAGCTCATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTCTTGACCTATGTGGGACAAT
TCTATCAAGAAAAATCTCACCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAAGCTGTCAAGGCTTTG
GTGGATACCAAGATTCTCAAACCCCAACGTGGAGAGAAAAAACAGCTGGTCAATCTAGCCATAAAAAATGCTCGTGTTAG
TCTAGAGCAGAAGTTCAATCTGCTAGAAAAATCAGTCGAAAAGACCCAAGGAGCTATTGAAAATCTAGGACGTTTGCTCC
AAATTCCGACTCCAGTTCGCATCGAGTCCTTCGATAACTCCAACATCATGGGGACCAGTCCTGTTTCAGCCATGGTGGTC
TTTGTTAACGGCAGGCCAAGTAAAAAAGATTACCGTAAGTACAAGATAAAAACCGTTGTTGGGCCGGACGACTATGCTAG
TATGAGAGAAGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATTGCTAAGCAAGTCATCCAAGAGGAACTGGGCTTGGATATTCCAATTGCTGGGCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTTGAGGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCTATCACTTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGACGGTCTGGGACCTAAACGCAAGCAGAATCTTATGAAGCATTTCAAGTCTTTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGGGTACCTAGAGTCGTTGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATGAAC
CATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(196-228)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

98.86

100

0.989
  uvrC Streptococcus pneumoniae R6

98.371

100

0.984
  uvrC Streptococcus pneumoniae D39

98.371

100

0.984