Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E4F32_RS09205 Genome accession   NZ_CP038180
Coordinates   1906722..1907378 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1901722..1912378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4F32_RS09175 (E4F32_09175) dcyD 1902602..1903588 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  E4F32_RS09180 (E4F32_09180) tcyL 1903603..1904271 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  E4F32_RS09185 (E4F32_09185) tcyN 1904268..1905020 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E4F32_RS09190 (E4F32_09190) sdiA 1905250..1905972 (+) 723 WP_001154275.1 transcriptional regulator SdiA -
  E4F32_RS09195 (E4F32_09195) yecF 1906039..1906263 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  E4F32_RS09200 (E4F32_09200) yecU 1906250..1906426 (-) 177 WP_032160694.1 protein YecU -
  E4F32_RS09205 (E4F32_09205) letA 1906722..1907378 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E4F32_RS09210 (E4F32_09210) uvrC 1907375..1909207 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E4F32_RS09215 (E4F32_09215) pgsA 1909264..1909812 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E4F32_RS09235 (E4F32_09235) yecA 1910462..1911127 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=309701 E4F32_RS09205 WP_000611328.1 1906722..1907378(+) (letA) [Escherichia coli strain]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=309701 E4F32_RS09205 WP_000611328.1 1906722..1907378(+) (letA) [Escherichia coli strain]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment