Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   DD548_RS12475 Genome accession   NZ_CP031673
Coordinates   2374949..2375518 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain MOZ66     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2369949..2380518
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DD548_RS12430 (DD548_12430) - 2370422..2371030 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  DD548_RS12435 (DD548_12435) rplL 2371205..2371573 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  DD548_RS12440 (DD548_12440) rplJ 2371616..2372116 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  DD548_RS12450 (DD548_12450) rplA 2372388..2373080 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  DD548_RS12455 (DD548_12455) rplK 2373288..2373710 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  DD548_RS12460 (DD548_12460) nusG 2373892..2374440 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  DD548_RS12465 (DD548_12465) secE 2374453..2374635 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  DD548_RS12470 (DD548_12470) rpmG 2374691..2374834 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  DD548_RS12475 (DD548_12475) sigH 2374949..2375518 (-) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  DD548_RS12480 (DD548_12480) - 2375599..2376123 (-) 525 WP_000664738.1 NYN domain-containing protein -
  DD548_RS12485 (DD548_12485) rlmB 2376123..2376869 (-) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  DD548_RS12490 (DD548_12490) - 2376877..2377281 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  DD548_RS12495 (DD548_12495) cysS 2377274..2378674 (-) 1401 WP_000631963.1 cysteine--tRNA ligase -
  DD548_RS12500 (DD548_12500) cysE 2378658..2379305 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=309682 DD548_RS12475 WP_000872873.1 2374949..2375518(-) (sigH) [Staphylococcus aureus strain MOZ66]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=309682 DD548_RS12475 WP_000872873.1 2374949..2375518(-) (sigH) [Staphylococcus aureus strain MOZ66]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment