Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   E3C75_RS09710 Genome accession   NZ_CP038020
Coordinates   1853926..1854570 (-) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1848926..1859570
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS09685 - 1851029..1852027 (-) 999 WP_111679664.1 NAD(P)/FAD-dependent oxidoreductase -
  E3C75_RS09690 trmD 1852029..1852748 (-) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  E3C75_RS09695 rimM 1852738..1853256 (-) 519 WP_084828975.1 ribosome maturation factor RimM -
  E3C75_RS09710 vraR 1853926..1854570 (-) 645 WP_002951384.1 response regulator transcription factor Regulator
  E3C75_RS09715 - 1854560..1855570 (-) 1011 WP_100262586.1 sensor histidine kinase -
  E3C75_RS09720 liaF 1855567..1856265 (-) 699 WP_014621793.1 cell wall-active antibiotics response protein LiaF -
  E3C75_RS11875 - 1856520..1856687 (-) 168 WP_014727613.1 potassium channel family protein -
  E3C75_RS09730 stkP/pknB 1857323..1859194 (-) 1872 WP_084826071.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=309261 E3C75_RS09710 WP_002951384.1 1853926..1854570(-) (vraR) [Streptococcus thermophilus strain ATCC 19258]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=309261 E3C75_RS09710 WP_002951384.1 1853926..1854570(-) (vraR) [Streptococcus thermophilus strain ATCC 19258]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGATAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379

Multiple sequence alignment