Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   E3C75_RS09060 Genome accession   NZ_CP038020
Coordinates   1720547..1722334 (-) Length   595 a.a.
NCBI ID   WP_100262502.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1715547..1727334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS09040 - 1716511..1717151 (-) 641 Protein_1738 DNA alkylation repair protein -
  E3C75_RS09045 - 1717343..1717855 (-) 513 WP_011681320.1 GNAT family N-acetyltransferase -
  E3C75_RS09050 - 1718133..1718815 (+) 683 Protein_1740 ISL3 family transposase -
  E3C75_RS09055 cls 1718908..1720458 (-) 1551 WP_172451571.1 cardiolipin synthase -
  E3C75_RS09060 uvrC 1720547..1722334 (-) 1788 WP_100262502.1 excinuclease ABC subunit UvrC Machinery gene
  E3C75_RS09065 - 1722394..1723089 (-) 696 Protein_1743 YjjG family noncanonical pyrimidine nucleotidase -
  E3C75_RS09070 - 1723389..1723817 (+) 429 WP_111679639.1 biotin transporter BioY -
  E3C75_RS09075 - 1724058..1724684 (-) 627 WP_111679640.1 ABC transporter permease -
  E3C75_RS09080 - 1724689..1725444 (-) 756 WP_014727588.1 ABC transporter ATP-binding protein -
  E3C75_RS09085 - 1725456..1726373 (-) 918 WP_014727589.1 glycine betaine ABC transporter substrate-binding protein -
  E3C75_RS09090 - 1726370..1727014 (-) 645 WP_223899667.1 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68683.04 Da        Isoelectric Point: 9.3843

>NTDB_id=309259 E3C75_RS09060 WP_100262502.1 1720547..1722334(-) (uvrC) [Streptococcus thermophilus strain ATCC 19258]
MNDLIKHKLELLPNNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGYDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPREIFIPGDIDQESVEAL
VGDEVKIFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=309259 E3C75_RS09060 WP_100262502.1 1720547..1722334(-) (uvrC) [Streptococcus thermophilus strain ATCC 19258]
ATGAACGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAACCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTTATGATGATAAAATCGTTAACCAGCTTAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGTGCAGCGGAGTATCGCGATTTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
GAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTGACCTATATGGGTCAAT
TTTACCTGGATAGTCGTCATCTTAAGCCTAGGGAAATTTTTATTCCTGGAGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGATTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCCTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACGGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-590)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrB/uvrC motif (UVR)

(196-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.311

99.328

0.758
  uvrC Streptococcus pneumoniae R6

75.973

99.328

0.755
  uvrC Streptococcus pneumoniae D39

75.973

99.328

0.755

Multiple sequence alignment