Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   E3C75_RS07115 Genome accession   NZ_CP038020
Coordinates   1339712..1341556 (+) Length   614 a.a.
NCBI ID   WP_172451564.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain ATCC 19258     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1334712..1346556
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3C75_RS07105 prx 1337592..1337780 (+) 189 WP_003045927.1 hypothetical protein Regulator
  E3C75_RS07110 - 1337962..1339710 (+) 1749 WP_111679566.1 type IA DNA topoisomerase -
  E3C75_RS07115 clpE 1339712..1341556 (+) 1845 WP_172451564.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  E3C75_RS07120 - 1341649..1341996 (+) 348 WP_000791789.1 TrbC/VirB2 family protein -
  E3C75_RS07125 - 1342007..1343080 (+) 1074 WP_111679568.1 hypothetical protein -
  E3C75_RS07130 - 1343100..1343882 (+) 783 WP_111679569.1 LPXTG cell wall anchor domain-containing protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 68688.72 Da        Isoelectric Point: 4.9348

>NTDB_id=309245 E3C75_RS07115 WP_172451564.1 1339712..1341556(+) (clpE) [Streptococcus thermophilus strain ATCC 19258]
MDDELKTPYLDKYTDNLSAKVAKKSDDYQVYGRDKEVKAVIISLLRRTKNNPILVGEAGVGKTAIVEGLTLAIMRGQVPE
PLKGLTVRSLELSSLMSGEDGGFIAKFKKIIEEMVATRGRNLLFVDEFHTIVGAGSQDGQALDAGNVIKPVLARGDIQLI
GATTLDEFHDYVETDRALERRMQPVMVEEPTIPQAISIIDQAKIIYEKFHGIQISSEAVKQAVRLSVRYLTDRFLPDKAF
DLIDEAATIASAEGKDSITEEDIAQVLKDKTGIPVTTILKGDQERLDGLKEKLMNRVKGQEDAIDAIVDAVTIAQAGLQD
ENKPISSFMFLGPTGVGKTELSKALAEALFDDENAMIRFDMSEFKEKEDAAKLIGNRATKTKGQLTQAVKQKPYCVVLLD
EVEKADGEVMDLFLQVLDDGRLTDSSGRLISFKNTIVIMTTNIGAKKIINKWELKGSFQHLTERDRQQFEKSMISELETE
FRPEFLNRIENKLIFNLLEREIIEKIAEKNLSEIEDRMRRKNMTLSYEPSLIQYLSDVGTDVKNGARPLERLIKRKVLAP
ISAKSLSLDKSRQTYNIHLWVEGEAPDGQHRKDLRQIQLDVEGEIGEEVAALFS

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=309245 E3C75_RS07115 WP_172451564.1 1339712..1341556(+) (clpE) [Streptococcus thermophilus strain ATCC 19258]
GTGGACGATGAATTGAAGACCCCCTATCTTGATAAATACACTGATAATTTGTCAGCTAAGGTTGCTAAAAAATCAGATGA
TTACCAAGTTTATGGCCGTGATAAGGAAGTAAAAGCGGTCATTATCTCTCTTCTCAGACGAACTAAAAATAATCCTATCT
TAGTAGGAGAAGCTGGAGTTGGGAAAACAGCTATTGTGGAAGGCCTAACGCTTGCTATTATGCGTGGTCAAGTTCCTGAA
CCTTTAAAAGGGTTAACAGTTCGCTCTCTGGAACTCTCTAGCTTGATGAGTGGGGAAGATGGTGGCTTTATTGCCAAGTT
TAAGAAGATTATTGAAGAGATGGTTGCGACACGTGGCCGTAATCTTCTCTTTGTAGATGAATTTCATACTATCGTTGGTG
CAGGTAGCCAGGATGGTCAAGCCCTCGATGCAGGAAATGTGATTAAACCAGTTTTAGCACGTGGGGATATTCAGCTGATT
GGTGCCACTACCCTAGATGAGTTTCATGACTATGTAGAGACTGATAGAGCCTTGGAACGTCGGATGCAACCAGTCATGGT
AGAAGAGCCCACCATTCCACAAGCCATATCCATTATTGATCAGGCCAAAATAATTTATGAGAAATTTCATGGGATTCAAA
TTTCTTCTGAAGCTGTGAAACAAGCGGTACGTTTATCTGTTCGTTATCTAACAGATCGCTTTCTGCCAGACAAAGCTTTT
GATTTGATTGATGAAGCAGCAACCATAGCTTCAGCTGAAGGAAAAGACAGTATTACAGAAGAGGATATTGCCCAGGTCTT
GAAGGATAAAACTGGTATTCCTGTCACTACAATATTAAAAGGTGATCAGGAACGCTTAGATGGTCTGAAGGAAAAATTAA
TGAATCGTGTCAAAGGGCAAGAGGATGCTATTGATGCCATTGTGGACGCTGTCACGATTGCTCAAGCTGGATTGCAAGAT
GAAAATAAACCGATTTCGTCATTCATGTTCCTGGGCCCAACAGGTGTTGGTAAAACTGAGTTATCCAAGGCTTTAGCTGA
AGCACTCTTTGATGATGAAAATGCCATGATTCGTTTTGATATGTCTGAGTTCAAAGAGAAAGAAGATGCAGCTAAATTGA
TTGGTAATCGTGCAACGAAAACAAAAGGGCAGCTGACACAGGCTGTAAAACAAAAGCCTTATTGTGTTGTGTTGCTAGAT
GAGGTTGAAAAGGCTGATGGTGAAGTTATGGATCTTTTTCTTCAGGTGCTAGATGATGGTCGTTTAACAGATAGTTCAGG
ACGTTTGATTAGCTTCAAAAATACTATTGTCATTATGACCACTAATATTGGAGCCAAAAAGATTATCAATAAATGGGAGT
TGAAGGGGAGTTTCCAGCATTTAACAGAACGTGATAGGCAACAATTTGAGAAGTCAATGATTAGTGAACTTGAAACTGAG
TTTAGACCAGAGTTCCTTAATCGTATTGAAAATAAGCTTATCTTCAATCTTTTGGAACGAGAAATTATTGAAAAGATTGC
AGAAAAAAACTTGTCTGAAATTGAAGATAGAATGAGGCGTAAAAATATGACCCTCTCATATGAGCCTAGTTTAATTCAGT
ATTTATCTGATGTAGGAACTGATGTAAAAAACGGCGCACGTCCCTTAGAGCGTTTGATTAAAAGAAAAGTTTTAGCTCCG
ATTTCAGCTAAAAGCCTTTCTTTAGATAAAAGTAGGCAAACCTACAATATTCATCTATGGGTTGAGGGAGAGGCACCAGA
TGGCCAACATCGAAAAGATTTGAGACAAATTCAGCTAGATGTTGAAGGAGAAATTGGAGAAGAAGTTGCTGCTCTTTTCA
GCTGA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(53-165)

AAA lid domain (AAA_lid_9)

(192-268)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(498-567)

AAA domain (Cdc48 subfamily) (AAA_2)

(323-490)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Bacillus subtilis subsp. subtilis str. 168

37.931

100

0.412
  clpE Streptococcus pneumoniae TIGR4

42.353

96.906

0.41
  clpE Streptococcus pneumoniae R6

41.556

98.371

0.409
  clpE Streptococcus pneumoniae D39

41.556

98.371

0.409
  clpE Streptococcus pneumoniae Rx1

41.556

98.371

0.409
  clpE Streptococcus mutans UA159

41.186

98.86

0.407
  clpC Lactococcus lactis subsp. cremoris KW2

40.558

99.186

0.402
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

39.005

100

0.396
  clpC Streptococcus pneumoniae D39

40.541

96.417

0.391
  clpC Streptococcus pneumoniae Rx1

40.541

96.417

0.391
  clpC Streptococcus pneumoniae TIGR4

40.541

96.417

0.391
  clpC Streptococcus thermophilus LMD-9

40.236

96.743

0.389
  clpC Streptococcus thermophilus LMG 18311

40.067

96.743

0.388
  clpC Streptococcus mutans UA159

39.43

97.068

0.383

Multiple sequence alignment