Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E1J55_RS09395 Genome accession   NZ_CP037903
Coordinates   1967967..1968623 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain LHM10-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1962967..1973623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1J55_RS09360 dcyD 1963846..1964832 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  E1J55_RS09365 tcyL 1964847..1965515 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  E1J55_RS09370 tcyN 1965512..1966264 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E1J55_RS09375 sdiA 1966494..1967216 (+) 723 WP_001154258.1 transcriptional regulator SdiA -
  E1J55_RS09380 yecF 1967284..1967508 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  E1J55_RS09385 yecU 1967495..1967671 (-) 177 WP_001302050.1 protein YecU -
  E1J55_RS26045 - 1967709..1967825 (-) 117 WP_089601844.1 transcriptional regulator -
  E1J55_RS09395 letA 1967967..1968623 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E1J55_RS09400 uvrC 1968620..1970452 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E1J55_RS09405 pgsA 1970509..1971057 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E1J55_RS09425 yecA 1971706..1972371 (+) 666 WP_063100087.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=308599 E1J55_RS09395 WP_000611335.1 1967967..1968623(+) (letA) [Escherichia coli strain LHM10-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=308599 E1J55_RS09395 WP_000611335.1 1967967..1968623(+) (letA) [Escherichia coli strain LHM10-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTTGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
AATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment