Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E1A98_RS02800 Genome accession   NZ_CP037857
Coordinates   564239..564895 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli BW25113 strain AM187     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 559239..569895
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1A98_RS02770 (E1A98_09905) dcyD 560118..561104 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  E1A98_RS02775 (E1A98_09900) tcyL 561119..561787 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  E1A98_RS02780 (E1A98_09895) tcyN 561784..562536 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E1A98_RS02785 (E1A98_09890) sdiA 562766..563488 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  E1A98_RS02790 (E1A98_09885) yecF 563556..563780 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  E1A98_RS02795 (E1A98_09880) yecU 563767..563943 (-) 177 WP_000590347.1 protein YecU -
  E1A98_RS22510 - 564026..564097 (-) 72 Protein_546 transcriptional regulator -
  E1A98_RS02800 (E1A98_09875) letA 564239..564895 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E1A98_RS02805 (E1A98_09870) uvrC 564892..566724 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E1A98_RS02810 (E1A98_09865) pgsA 566781..567329 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E1A98_RS02830 (E1A98_09845) yecA 567979..568644 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=308488 E1A98_RS02800 WP_000611335.1 564239..564895(+) (letA) [Escherichia coli BW25113 strain AM187]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=308488 E1A98_RS02800 WP_000611335.1 564239..564895(+) (letA) [Escherichia coli BW25113 strain AM187]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486