Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E0708_RS23515 Genome accession   NZ_CP037449
Coordinates   4930319..4930975 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ATCC 25922     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4925319..4935975
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0708_RS23485 (E0708_24200) yecA 4926571..4927236 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  E0708_RS23505 (E0708_24220) pgsA 4927885..4928433 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E0708_RS23510 (E0708_24225) uvrC 4928490..4930322 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E0708_RS23515 (E0708_24230) letA 4930319..4930975 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E0708_RS23520 (E0708_24235) yecU 4931271..4931447 (+) 177 WP_001304283.1 protein YecU -
  E0708_RS23525 (E0708_24240) yecF 4931434..4931658 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  E0708_RS23530 (E0708_24245) sdiA 4931726..4932448 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  E0708_RS23535 (E0708_24250) tcyN 4932678..4933430 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E0708_RS23540 (E0708_24255) tcyL 4933427..4934095 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  E0708_RS23545 (E0708_24260) dcyD 4934110..4935096 (-) 987 WP_001128236.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=308477 E0708_RS23515 WP_000611328.1 4930319..4930975(-) (letA) [Escherichia coli strain ATCC 25922]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=308477 E0708_RS23515 WP_000611328.1 4930319..4930975(-) (letA) [Escherichia coli strain ATCC 25922]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment