Detailed information NTG0308372

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: DZV37_RS05840
• Genome accession: NZ_CP031624
• Coordinates: 1141572..1142801 (-)
• Length: 409 a.a.
• NCBI ID: WP_047298102.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS28650
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1136572..1147801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DZV37_RS05820 (DZV37_05820)	rpiA	1136854..1137537 (-)	684	WP_011284704.1	ribose-5-phosphate isomerase RpiA	-
DZV37_RS05825 (DZV37_05825)	-	1137915..1140014 (+)	2100	WP_011284703.1	ATP-dependent Clp protease ATP-binding subunit	-
DZV37_RS05830 (DZV37_05830)	-	1140072..1140815 (-)	744	WP_002984942.1	hypothetical protein	-
DZV37_RS05835 (DZV37_05835)	yihA	1140963..1141562 (-)	600	WP_011284702.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
DZV37_RS05840 (DZV37_05840)	clpX	1141572..1142801 (-)	1230	WP_047298102.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
DZV37_RS05850 (DZV37_05850)	-	1143121..1143618 (-)	498	WP_011284701.1	dihydrofolate reductase	-
DZV37_RS05855 (DZV37_05855)	-	1143698..1144537 (-)	840	WP_011017679.1	thymidylate synthase	-
DZV37_RS05860 (DZV37_05860)	-	1144746..1145921 (+)	1176	WP_021340971.1	hydroxymethylglutaryl-CoA synthase	-
DZV37_RS05865 (DZV37_05865)	-	1145908..1147185 (+)	1278	WP_011284699.1	hydroxymethylglutaryl-CoA reductase, degradative	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45021.46 Da
• Isoelectric Point: 4.5775

>NTDB_id=308372 DZV37_RS05840 WP_047298102.1 1141572..1142801(-) (clpX) [Streptococcus pyogenes strain MGAS28650]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFTIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=308372 DZV37_RS05840 WP_047298102.1 1141572..1142801(-) (clpX) [Streptococcus pyogenes strain MGAS28650]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTACTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAGCGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572