Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EZV63_RS18630 Genome accession   NZ_CP036534
Coordinates   4186554..4187240 (+) Length   228 a.a.
NCBI ID   WP_037766288.1    Uniprot ID   A0ABS7W345
Organism   Streptomyces sp. VN1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4181554..4192240
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZV63_RS18610 (EZV63_18855) - 4181677..4182579 (+) 903 WP_031043667.1 alpha/beta hydrolase -
  EZV63_RS18615 (EZV63_18860) - 4182800..4183789 (+) 990 WP_166624531.1 alpha/beta hydrolase -
  EZV63_RS18620 (EZV63_18865) - 4183782..4185071 (+) 1290 WP_037766291.1 acyltransferase -
  EZV63_RS18625 (EZV63_18870) - 4185064..4186557 (+) 1494 WP_051159682.1 sensor histidine kinase -
  EZV63_RS18630 (EZV63_18875) vraR 4186554..4187240 (+) 687 WP_037766288.1 response regulator transcription factor Regulator
  EZV63_RS18635 (EZV63_18880) - 4187253..4188671 (+) 1419 WP_037766285.1 histidine kinase -
  EZV63_RS18640 (EZV63_18885) vraR 4188668..4189342 (+) 675 WP_166624532.1 response regulator transcription factor Regulator
  EZV63_RS18645 (EZV63_18895) - 4189517..4190791 (+) 1275 WP_228773761.1 cytochrome P450 -
  EZV63_RS18650 (EZV63_18900) - 4190774..4191049 (-) 276 WP_031043642.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 24655.33 Da        Isoelectric Point: 5.1349

>NTDB_id=308353 EZV63_RS18630 WP_037766288.1 4186554..4187240(+) (vraR) [Streptomyces sp. VN1]
MTTSGNGRVIRVLIADDQQMVRQGFTVLLNTQPDIEVIGQAVHGLDAVAKVADLSPDVVLMDIRMPELDGIEATRRITGS
TPDIRVLVLTTFDLDEYVYEALRAGASGFLLKDASADQLADAVRVVAAGDALLAPGITRRLIAEFSRLDDRPRGPLKARV
GDLTERETEVLALIAQGLSNAEIARRLVVAEQTVKTHVGRILVKLGLRDRTQAAVFAYESGLVRPSGY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=308353 EZV63_RS18630 WP_037766288.1 4186554..4187240(+) (vraR) [Streptomyces sp. VN1]
ATGACGACCAGCGGCAACGGCCGTGTGATCCGCGTGCTGATCGCCGACGACCAGCAGATGGTCCGGCAGGGATTCACCGT
GCTGCTCAACACCCAGCCCGACATCGAGGTGATCGGACAGGCGGTGCACGGCCTGGACGCCGTCGCGAAGGTCGCCGACC
TGTCCCCGGACGTCGTCCTGATGGACATCCGCATGCCCGAGCTGGACGGCATCGAGGCCACCCGCCGGATCACCGGTTCG
ACCCCGGACATCAGGGTGCTCGTACTGACCACCTTCGACCTCGACGAGTACGTGTACGAGGCGCTGCGGGCCGGGGCCTC
CGGGTTCCTGCTGAAGGACGCGTCGGCCGACCAGCTGGCCGACGCGGTCCGGGTGGTGGCGGCCGGGGACGCCCTGCTCG
CGCCGGGTATCACCCGGCGTCTGATCGCCGAGTTCTCCCGGCTGGACGACCGCCCGCGCGGCCCGCTGAAGGCCCGCGTC
GGCGACCTGACCGAGCGGGAGACGGAGGTCCTCGCCCTGATCGCCCAGGGCCTGTCCAACGCGGAGATCGCCCGGCGTCT
GGTGGTCGCCGAGCAGACGGTGAAGACCCACGTCGGCAGGATCCTGGTGAAGCTGGGCCTGAGGGACCGCACCCAGGCGG
CGGTCTTCGCCTACGAGTCGGGCCTGGTGCGCCCCTCGGGATACTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(163-217)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.981

94.737

0.417
  degU Bacillus subtilis subsp. subtilis str. 168

39.91

97.807

0.39

Multiple sequence alignment