Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   AB849_RS05800 Genome accession   NZ_CP036487
Coordinates   1121228..1124107 (+) Length   959 a.a.
NCBI ID   WP_037997785.1    Uniprot ID   A0ABS0QG39
Organism   Thermoactinomyces vulgaris strain CDF     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1116228..1129107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB849_RS05785 (AB849_005785) - 1116445..1117896 (+) 1452 WP_049720670.1 S41 family peptidase -
  AB849_RS05790 (AB849_005790) - 1117975..1119093 (+) 1119 WP_037997781.1 PDZ domain-containing protein -
  AB849_RS05795 (AB849_005795) uvrB 1119245..1121224 (+) 1980 WP_037997783.1 excinuclease ABC subunit UvrB Machinery gene
  AB849_RS05800 (AB849_005800) uvrA 1121228..1124107 (+) 2880 WP_037997785.1 excinuclease ABC subunit UvrA Machinery gene
  AB849_RS05805 (AB849_005805) - 1124191..1124400 (+) 210 WP_037997788.1 alpha/beta-type small acid-soluble spore protein -
  AB849_RS05810 (AB849_005810) - 1124420..1124650 (-) 231 WP_037993289.1 DUF2553 family protein -
  AB849_RS05815 (AB849_005815) - 1124945..1125355 (+) 411 WP_049720669.1 DUF302 domain-containing protein -
  AB849_RS05820 (AB849_005820) - 1125568..1125903 (+) 336 WP_037993291.1 phage holin family protein -
  AB849_RS05825 (AB849_005825) - 1125943..1126464 (-) 522 WP_037993292.1 DUF84 family protein -
  AB849_RS05830 (AB849_005830) - 1126430..1127077 (-) 648 WP_049720668.1 class D sortase -
  AB849_RS05835 (AB849_005835) hprK 1127326..1128261 (+) 936 WP_037993293.1 HPr(Ser) kinase/phosphatase -

Sequence

Protein


Download         Length: 959 a.a.        Molecular weight: 106418.98 Da        Isoelectric Point: 8.3265

>NTDB_id=307905 AB849_RS05800 WP_037997785.1 1121228..1124107(+) (uvrA) [Thermoactinomyces vulgaris strain CDF]
MSQEKIVVRGARVHNLKNIDVTIPRDQFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDGIDG
LSPAISIDQKTTSRNPRSTVGTVTEIYDYLRLLYARVGHAYCPVHGIEIKSQTVQQMVDRIMELPERSRIQVLAPVVKGR
KGEHVKLLKDISRQGYVRVRIDGELRDLSEEIKLEKNKKHTIEVVVDRIIVKPGVNTRLTDSVETALAISDGEVLVDVIG
GDELLFSSKLACPECGFSIEELSPRMFSFNSPYGACPACDGLGNRLVIDPQLVIPDPSLSLNEGAIEPWSSSNGNHYYEQ
LLKAACDHFQIDMDKPFQDLSQKEKDILLYGSDERFPFRYVRNSGFEREAMARFDGVVGHLNRRFKETGSDMVREYLETY
MTTKSCPSCKGARLKKEILHIYVGGKNIDEVTRLSIKEALEFFQNLSLSDKENQIAYQVLKEIKSRLGFLVNVGLGYLSL
SRAAGTLSGGEAQRIRLATQIGSKLMGVLYILDEPSIGLHQRDNNRLIATLKEMRDLGNTLIVVEHDEDTMLACDYIIDI
GPGAGAHGGKVVAAGTPQELMENEKSLTGEYLSGRRFIPVPQKRREPNGKWIKVSGARENNLKNIDVAFPLGVFTCVTGV
SGSGKSTLVNEILLKGLARRLGKAKTVPGKHKKIEGAEHLNKIINIDQSPIGRTPRSNPATYTGVFDDIREVFASTPEAK
VRGYKKGRFSFNVKGGRCEACRGDGIIKIEMHFLPDVYVPCEQCKGKRYNRETLEVKYKGKSISDVLEMTVEESLDFFAN
IPRIQRKLQTLYDVGLGYIKLGQPATQLSGGEAQRVKLASELYKRSQGRTLYVLDEPTTGLHIDDIARLLKVLERLVENG
DTVVVIEHNLDVIKTADYLIDLGPEGGSGGGTIVAKGTPEEVAKSKGSYTGQFLAPILERDKKRMETLLAKREETATPK

Nucleotide


Download         Length: 2880 bp        

>NTDB_id=307905 AB849_RS05800 WP_037997785.1 1121228..1124107(+) (uvrA) [Thermoactinomyces vulgaris strain CDF]
ATGTCGCAAGAAAAGATTGTCGTTCGCGGTGCACGGGTGCATAATCTGAAAAACATTGATGTGACGATTCCGCGTGATCA
GTTTGTTGTCATCACGGGGTTGAGCGGTTCCGGAAAGTCCTCACTTGCGTTTGACACCATTTATGCCGAAGGGCAACGTC
GTTATGTCGAATCGCTTTCGGCTTATGCCCGCCAGTTTTTGGGGCAAATGGACAAGCCGGATGTCGATGGGATTGACGGG
TTGTCCCCGGCGATCTCCATCGACCAGAAAACGACGAGCCGCAATCCCCGTTCCACGGTCGGAACCGTGACCGAGATTTA
CGATTACCTGCGCTTGCTCTATGCGCGGGTGGGACATGCTTATTGTCCGGTGCATGGAATCGAGATTAAATCGCAAACCG
TTCAGCAAATGGTGGACCGGATCATGGAATTGCCGGAGCGTTCCCGGATTCAGGTTTTGGCACCGGTCGTCAAAGGGCGA
AAAGGGGAGCATGTCAAGCTTTTAAAAGATATCAGCCGCCAAGGGTATGTGCGTGTCCGGATTGACGGGGAACTCCGGGA
TTTGTCCGAAGAGATCAAACTGGAGAAAAACAAAAAGCATACCATCGAAGTGGTGGTGGACCGGATCATCGTCAAACCGG
GCGTGAACACGCGGCTTACGGATTCCGTCGAGACCGCTCTGGCAATCAGTGACGGTGAAGTGTTGGTCGATGTGATCGGC
GGGGACGAGTTGTTGTTCAGTTCCAAGCTGGCTTGTCCGGAGTGCGGCTTCAGCATTGAGGAATTGTCTCCGCGCATGTT
CTCTTTTAACAGCCCGTACGGCGCTTGTCCGGCTTGTGACGGACTGGGAAACCGGTTGGTGATCGACCCGCAGCTGGTGA
TTCCCGATCCGTCCCTTTCCCTGAATGAAGGAGCGATTGAACCCTGGTCTTCTTCCAACGGCAATCATTATTACGAGCAA
CTGTTGAAAGCCGCTTGCGACCATTTCCAAATTGACATGGATAAGCCGTTTCAGGATTTAAGCCAAAAGGAAAAGGATAT
TCTCCTTTACGGTTCCGATGAACGGTTTCCTTTCAGATATGTGAGAAACAGCGGTTTTGAACGGGAAGCCATGGCCCGGT
TTGACGGGGTGGTGGGACATTTGAACCGCCGTTTTAAAGAAACCGGTTCCGACATGGTGCGCGAGTATTTGGAAACGTAT
ATGACAACCAAGTCTTGCCCTTCCTGCAAGGGGGCCCGCCTGAAAAAAGAGATTCTTCATATCTACGTCGGCGGAAAAAA
CATCGATGAGGTCACTCGTCTTTCGATCAAAGAGGCACTGGAATTTTTCCAAAACCTGTCTTTGTCGGACAAGGAAAACC
AAATCGCTTATCAAGTGTTAAAAGAAATTAAAAGCCGGCTCGGTTTTTTGGTCAATGTGGGACTCGGTTATCTGAGTTTG
TCCCGCGCGGCCGGGACGTTGTCGGGAGGAGAAGCGCAACGGATTCGCCTGGCGACCCAGATCGGTTCCAAATTGATGGG
GGTTTTGTATATTCTGGATGAGCCGAGCATCGGCCTCCATCAGAGAGATAACAACCGCTTGATTGCCACCCTCAAGGAGA
TGAGGGATTTGGGGAATACCCTGATTGTGGTGGAGCATGATGAAGACACGATGTTGGCTTGCGATTACATCATCGATATC
GGTCCCGGTGCCGGAGCCCACGGGGGAAAAGTGGTTGCTGCCGGCACGCCGCAGGAATTGATGGAAAATGAAAAATCGTT
GACAGGGGAATACTTAAGCGGCCGCCGTTTCATTCCCGTGCCACAGAAGCGGAGAGAGCCGAACGGCAAATGGATCAAAG
TGTCGGGAGCACGGGAAAATAACTTGAAAAATATCGATGTTGCCTTTCCTCTCGGCGTATTCACCTGTGTGACGGGCGTT
TCCGGTTCGGGAAAAAGTACACTGGTTAATGAAATTTTGTTAAAAGGTTTGGCGCGCCGGTTGGGCAAAGCCAAAACGGT
GCCCGGCAAGCACAAAAAAATCGAAGGCGCCGAACATTTAAATAAAATCATTAACATCGACCAATCTCCGATCGGGAGAA
CACCGCGTTCCAATCCTGCAACGTACACCGGGGTGTTTGATGATATCCGCGAAGTGTTTGCATCCACGCCGGAAGCCAAG
GTGAGAGGCTACAAGAAAGGGCGTTTCAGTTTCAATGTCAAAGGCGGACGGTGCGAGGCCTGCCGCGGGGACGGTATTAT
TAAAATTGAAATGCATTTTCTGCCGGATGTTTATGTACCGTGTGAACAATGCAAAGGGAAACGGTATAACCGGGAAACCT
TGGAAGTGAAATACAAAGGAAAAAGCATTTCGGATGTCTTGGAAATGACGGTGGAGGAATCCTTGGATTTCTTTGCGAAT
ATTCCCCGGATCCAACGGAAATTGCAAACCCTTTATGACGTGGGGCTGGGGTATATCAAACTGGGACAGCCGGCCACGCA
ATTGTCCGGGGGGGAAGCCCAACGGGTGAAATTGGCTTCGGAGTTGTATAAACGGAGTCAAGGGCGGACGTTATATGTGC
TGGATGAACCCACCACCGGTCTTCACATCGATGATATCGCGCGGTTGCTCAAAGTGTTGGAGCGGCTGGTGGAAAACGGG
GACACGGTGGTCGTCATTGAGCATAATCTGGATGTGATTAAAACAGCGGACTATCTGATTGACCTGGGACCGGAAGGCGG
AAGCGGCGGGGGAACGATCGTTGCCAAAGGAACACCGGAAGAAGTGGCCAAGAGCAAAGGATCTTATACCGGACAATTCC
TGGCGCCGATTTTGGAAAGAGACAAAAAACGCATGGAAACCCTGCTGGCAAAACGGGAAGAGACCGCAACCCCAAAGTAA

Domains

Predicted by InterProScan.

UvrA DNA-binding domain (UvrA_DNA-bind)

(289-398)

ABC transporter (ABC_tran)

(622-858)

UvrA interaction domain (UvrA_inter)

(132-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

64.637

97.602

0.631
  uvrA Streptococcus pneumoniae TIGR4

64.637

97.602

0.631
  uvrA Streptococcus pneumoniae D39

64.637

97.602

0.631