Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   AB849_RS00770 Genome accession   NZ_CP036487
Coordinates   148653..150419 (-) Length   588 a.a.
NCBI ID   WP_255359646.1    Uniprot ID   -
Organism   Thermoactinomyces vulgaris strain CDF     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 143653..155419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB849_RS00750 (AB849_000750) - 145373..145546 (+) 174 WP_062842883.1 twin-arginine translocase TatA/TatE family subunit -
  AB849_RS00755 (AB849_000755) - 145543..147108 (-) 1566 WP_049719808.1 phytoene desaturase family protein -
  AB849_RS00760 (AB849_000760) - 147117..147878 (-) 762 WP_049719807.1 lysophospholipid acyltransferase family protein -
  AB849_RS00765 (AB849_000765) - 148083..148580 (-) 498 WP_037993345.1 DnaD domain protein -
  AB849_RS00770 (AB849_000770) uvrC 148653..150419 (-) 1767 WP_255359646.1 excinuclease ABC subunit UvrC Machinery gene
  AB849_RS00775 (AB849_000775) - 150657..151424 (+) 768 WP_049719805.1 hypothetical protein -
  AB849_RS00780 (AB849_000780) trxA 151488..151811 (-) 324 WP_049719804.1 thioredoxin -
  AB849_RS00785 (AB849_000785) - 151982..152968 (-) 987 WP_037993353.1 electron transfer flavoprotein subunit alpha/FixB family protein -
  AB849_RS00790 (AB849_000790) - 152988..153767 (-) 780 WP_037993355.1 electron transfer flavoprotein subunit beta/FixA family protein -
  AB849_RS00795 (AB849_000795) - 153798..154382 (-) 585 WP_037993357.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 588 a.a.        Molecular weight: 68069.70 Da        Isoelectric Point: 9.0527

>NTDB_id=307871 AB849_RS00770 WP_255359646.1 148653..150419(-) (uvrC) [Thermoactinomyces vulgaris strain CDF]
MEIKDKLSLLPEKPGCYLMLNQDQEVIYVGKAKNLRNRVRSYFTGSHDGKTQRLVMDIADFEYIVTSNHVEALILELNLI
KKHRPKYNVMLKDDKSYPYIRLTKEKHPRLEVTRNLKKDGSKYFGPYPHAGAAQHTKKLLDRLFPLRKCKTIPKRVCLYY
HMGQCLAPCEMDVDPDDYEKITKEIVRFLNGGVTELKKELQRKMEEAAENLEFEQAKEYRDLLLDIDSTIEKQNIVLPAQ
QNLDIFGYAAEKGWMCVQVFFVRQGKLIEREVSVFPHYHEAEEDFVSFVAQFYHEMPTLPKEIHLPRGVDPDILTKMLPE
VHIHVPRRGNKKNLVNMATENAEIALKERFQLLERDEQKTWNALEGLSRALGIGLPRRIEAFDNSNIQGTDPVSAMVCFI
DGKPAKKEYRKYRIRTVSGPNDVETMREVIRRRYTRVLKENRPLPDLVLVDGGKAQIHAAVDVLENELGLFIPVGGMVKD
DKHQTAKLMAGDPVEEVKLERGSDTFFLIQRIQEEVHRFAITFHRQVRGKSMFQSELDKIQGVGPKRKQLLYQHFGSIEN
MKKASIEEFRKAGIGDQLARTILKELNQ

Nucleotide


Download         Length: 1767 bp        

>NTDB_id=307871 AB849_RS00770 WP_255359646.1 148653..150419(-) (uvrC) [Thermoactinomyces vulgaris strain CDF]
TTGGAGATAAAAGACAAACTGTCTCTGTTGCCGGAAAAACCCGGTTGTTACTTGATGTTAAATCAAGACCAGGAAGTGAT
TTACGTCGGCAAGGCGAAAAATTTGCGAAACCGGGTTCGTTCTTATTTTACGGGGAGCCATGACGGAAAAACCCAACGCT
TGGTGATGGATATCGCCGATTTTGAGTACATTGTCACGTCCAATCACGTGGAGGCTTTGATTCTGGAGTTGAATTTGATC
AAAAAACACCGCCCGAAATATAACGTGATGTTAAAAGATGACAAATCGTACCCTTACATCCGGCTGACCAAAGAAAAACA
TCCCCGCCTGGAAGTGACCCGGAACTTAAAAAAGGATGGTTCCAAATACTTCGGACCTTATCCCCATGCCGGAGCGGCTC
AACACACCAAAAAGTTATTGGACCGCTTGTTTCCGCTGCGCAAGTGCAAAACAATCCCCAAACGGGTATGCCTGTATTAC
CATATGGGACAATGTCTGGCTCCTTGTGAAATGGATGTGGATCCGGACGATTACGAGAAAATAACGAAGGAAATCGTCCG
CTTTTTAAACGGGGGAGTTACGGAACTGAAAAAAGAATTGCAAAGAAAAATGGAAGAAGCAGCGGAAAACTTGGAGTTCG
AACAAGCCAAAGAGTACCGGGACCTGCTCTTGGATATTGACTCAACCATTGAAAAACAAAACATTGTCCTTCCCGCTCAA
CAGAATTTGGACATCTTCGGCTATGCGGCGGAAAAGGGCTGGATGTGTGTCCAGGTGTTTTTTGTGCGCCAGGGAAAATT
GATTGAACGGGAAGTATCGGTGTTTCCGCACTACCACGAGGCAGAAGAAGATTTTGTTTCTTTTGTCGCCCAGTTTTATC
ACGAAATGCCTACACTCCCGAAAGAAATTCATTTACCCCGAGGAGTGGATCCGGATATTCTCACAAAAATGCTTCCGGAA
GTTCACATTCATGTTCCCCGGCGCGGCAACAAAAAGAATCTGGTGAACATGGCCACCGAAAATGCGGAGATTGCCTTGAA
AGAACGTTTCCAATTGTTGGAGCGGGACGAGCAAAAAACGTGGAATGCGTTGGAAGGTTTGAGCCGGGCGCTTGGCATCG
GGTTGCCCCGCCGGATTGAAGCATTTGACAACTCCAATATCCAAGGGACCGATCCGGTGTCGGCGATGGTATGTTTTATC
GATGGAAAACCGGCCAAAAAAGAATACCGCAAATACCGGATCCGGACCGTTTCCGGCCCCAATGACGTGGAAACCATGCG
GGAAGTGATCCGGCGCCGTTATACGCGCGTTTTGAAAGAAAACCGTCCGTTGCCGGATTTGGTCTTGGTGGACGGCGGAA
AAGCGCAAATCCATGCGGCCGTGGATGTGTTGGAAAACGAATTGGGATTGTTTATCCCGGTCGGCGGCATGGTGAAAGAT
GACAAACACCAAACAGCCAAACTGATGGCCGGGGATCCGGTGGAGGAAGTGAAGCTGGAGCGGGGAAGCGACACTTTTTT
CCTGATCCAGCGCATTCAGGAAGAAGTACACCGCTTTGCCATCACGTTTCACCGGCAGGTTCGCGGCAAAAGCATGTTCC
AATCCGAATTGGATAAAATCCAGGGAGTCGGGCCGAAACGAAAGCAACTGCTTTATCAACATTTTGGATCCATTGAAAAC
ATGAAAAAAGCTTCCATTGAAGAGTTTCGGAAGGCGGGTATTGGCGATCAGCTGGCCCGGACCATTCTGAAGGAGTTAAA
CCAATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(195-224)

GIY-YIG catalytic domain (GIY-YIG)

(14-88)

Helix-hairpin-helix domain (HHH_5)

(536-586)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-521)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae R6

54.437

99.66

0.543
  uvrC Streptococcus pneumoniae D39

54.437

99.66

0.543
  uvrC Streptococcus pneumoniae TIGR4

54.266

99.66

0.541