Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   L3107_RS07895 Genome accession   NZ_CP031538
Coordinates   1554409..1555881 (-) Length   490 a.a.
NCBI ID   WP_063283897.1    Uniprot ID   -
Organism   Lactococcus cremoris strain 3107     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1549409..1560881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3107_RS07875 (L3107_1537) murG 1549722..1550795 (-) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -
  L3107_RS07880 (L3107_1538) murD 1551038..1552387 (-) 1350 WP_021165520.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  L3107_RS07885 (L3107_1539) - 1552556..1552897 (-) 342 WP_011676628.1 P-II family nitrogen regulator -
  L3107_RS07890 (L3107_1540) - 1552982..1554223 (-) 1242 WP_015082643.1 ammonium transporter -
  L3107_RS07895 (L3107_1541) covS 1554409..1555881 (-) 1473 WP_063283897.1 HAMP domain-containing histidine kinase Regulator
  L3107_RS07900 (L3107_1542) covR 1555894..1556586 (-) 693 WP_011676631.1 response regulator transcription factor Regulator
  L3107_RS07905 (L3107_1543) - 1556743..1557273 (-) 531 WP_011834860.1 DUF177 domain-containing protein -
  L3107_RS07910 (L3107_1544) - 1557406..1557651 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  L3107_RS07915 - 1557975..1558337 (-) 363 Protein_1548 TIGR02328 family protein -
  L3107_RS07920 (L3107_1546) - 1558574..1559485 (-) 912 Protein_1549 CHAP domain-containing protein -
  L3107_RS07925 (L3107_1547) - 1559578..1560414 (-) 837 WP_021165524.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55872.71 Da        Isoelectric Point: 4.7011

>NTDB_id=307354 L3107_RS07895 WP_063283897.1 1554409..1555881(-) (covS) [Lactococcus cremoris strain 3107]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRRDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNHWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKI

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=307354 L3107_RS07895 WP_063283897.1 1554409..1555881(-) (covS) [Lactococcus cremoris strain 3107]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACGTGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
ATTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCCAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTGGCTCGTTTAGCCGAAAATTATCAAGGAGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATATGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

HAMP domain (HAMP)

(208-258)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945

Multiple sequence alignment