Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   LR49_RS11185 Genome accession   NZ_CP031537
Coordinates   2132779..2133348 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain WCH-SK2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2127779..2138348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LR49_RS11160 (LR49_11160) cysE 2128992..2129639 (+) 648 WP_001838365.1 serine O-acetyltransferase -
  LR49_RS11165 (LR49_11165) cysS 2129623..2131023 (+) 1401 WP_000631964.1 cysteine--tRNA ligase -
  LR49_RS11170 (LR49_11170) - 2131016..2131420 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  LR49_RS11175 (LR49_11175) rlmB 2131428..2132174 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  LR49_RS11180 (LR49_11180) - 2132174..2132698 (+) 525 WP_000664738.1 NYN domain-containing protein -
  LR49_RS11185 (LR49_11185) sigH 2132779..2133348 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  LR49_RS11190 (LR49_11190) rpmG 2133463..2133606 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  LR49_RS11195 (LR49_11195) secE 2133662..2133844 (+) 183 WP_001074474.1 preprotein translocase subunit SecE -
  LR49_RS11200 (LR49_11200) nusG 2133857..2134405 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  LR49_RS11205 (LR49_11205) rplK 2134586..2135008 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  LR49_RS11210 (LR49_11210) rplA 2135216..2135908 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  LR49_RS11220 (LR49_11220) rplJ 2136180..2136680 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  LR49_RS11225 (LR49_11225) rplL 2136723..2137091 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  LR49_RS11230 (LR49_11230) - 2137266..2137874 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=307326 LR49_RS11185 WP_000872873.1 2132779..2133348(+) (sigH) [Staphylococcus aureus strain WCH-SK2]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=307326 LR49_RS11185 WP_000872873.1 2132779..2133348(+) (sigH) [Staphylococcus aureus strain WCH-SK2]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment