Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   SDEG_RS10145 Genome accession   NC_012891
Coordinates   2028448..2030430 (-) Length   660 a.a.
NCBI ID   WP_012767642.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis GGS_124     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2023448..2035430
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDEG_RS10120 (SDEG_2085) cinA 2024289..2025560 (-) 1272 WP_003058772.1 competence/damage-inducible protein A Machinery gene
  SDEG_RS10125 (SDEG_2086) - 2025684..2026037 (-) 354 WP_003058738.1 VOC family protein -
  SDEG_RS10130 (SDEG_2087) - 2026040..2026612 (-) 573 WP_003058799.1 DNA-3-methyladenine glycosylase I -
  SDEG_RS10135 (SDEG_2088) ruvA 2026622..2027215 (-) 594 WP_003058778.1 Holliday junction branch migration protein RuvA Machinery gene
  SDEG_RS10140 (SDEG_2089) - 2027217..2028437 (-) 1221 WP_003058727.1 MDR family MFS transporter -
  SDEG_RS10145 (SDEG_2090) hexB 2028448..2030430 (-) 1983 WP_012767642.1 DNA mismatch repair endonuclease MutL Machinery gene
  SDEG_RS10150 (SDEG_2091) hexA 2030558..2033113 (-) 2556 WP_012767643.1 DNA mismatch repair protein MutS Machinery gene
  SDEG_RS10155 (SDEG_2092) - 2033100..2033453 (-) 354 WP_012767644.1 YlbF family regulator -
  SDEG_RS10160 (SDEG_2093) argR 2033450..2033887 (-) 438 WP_003055516.1 arginine repressor -

Sequence

Protein


Download         Length: 660 a.a.        Molecular weight: 74561.92 Da        Isoelectric Point: 5.4680

>NTDB_id=30720 SDEG_RS10145 WP_012767642.1 2028448..2030430(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
MTKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAKSSQVTIDIEESGLKKIQITDNGEGMSPEDLPLSLRRHATSK
IKSQSDLFRIRTLGFRGEALPSVASISKITIKTATKEDNHGSLLVAIGGEIETLEETSTPVGTKIKVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVSFTLISDGRQLTQTSGTGDLRQAIAGIYGLNTAKKMIAISNADLDFEVSGYVSLP
ELTRANRNYMTILINGRYIKNFLLNRAILDGYGSKLMVGRFPIVVIDIQIDPYLADVNVHPTKQEVRISKERELMALIST
AISESLKEQDLIPDALENLAKSSTRHFSKPEQTQLPLQSKGLYYDPQRNDFFVKESDVSEKIPESNFHNTEIDKTVKDQR
TEQFPDLGENTGFSSVKRASRSQDEITDADHPGFDLKNKQKLSQMLTRLENEEQSVFPELDYFGQMHGTYLFAQGKDGLF
IIDQHAAQERVKYEYYRDKIGEVDSSLQQLLVPYLFEFSGSDFINLQEKMALLNEVGIFLEVYGHNTFILREHPIWMKEE
EIASGVYEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARNLLLQLAQCQNPYNCPHGRPVLINFSKADM
EKMFRRIQENHTSLRELGKY

Nucleotide


Download         Length: 1983 bp        

>NTDB_id=30720 SDEG_RS10145 WP_012767642.1 2028448..2030430(-) (hexB) [Streptococcus dysgalactiae subsp. equisimilis GGS_124]
ATGACAAAAATTATTGAATTACCAGAAGTTCTCGCCAACCAAATTGCAGCTGGTGAAGTTGTAGAAAGGCCAGCGAGTGT
TGTCAAGGAATTGGTTGAGAATGCTATCGATGCTAAGAGTAGCCAAGTCACCATTGATATTGAAGAGTCTGGTCTCAAAA
AGATACAGATTACGGACAATGGTGAAGGGATGTCGCCTGAAGACCTTCCTTTGAGTTTGCGGCGACATGCTACCAGTAAA
ATAAAAAGTCAAAGTGATCTCTTTCGAATTAGAACACTTGGTTTTAGGGGAGAAGCCTTACCATCGGTTGCTTCTATCAG
TAAAATCACAATAAAAACAGCTACTAAGGAAGATAATCACGGTTCTCTTTTAGTTGCTATCGGCGGAGAGATTGAAACGC
TCGAGGAAACGTCGACGCCTGTAGGTACCAAGATTAAGGTTGAAAACCTTTTTTATAACACGCCTGCTCGCCTCAAATAC
ATGAAAAGTTTACAGGCAGAGTTAGCCCATATTGTTGATGTGGTCAATCGTTTGAGTTTGGCACATCCAGAAGTTTCTTT
CACCCTTATTAGTGATGGCCGTCAATTAACTCAGACATCAGGGACGGGGGACCTGCGGCAGGCTATTGCAGGGATTTATG
GCTTGAATACTGCCAAAAAAATGATTGCTATTTCCAATGCCGATTTGGACTTTGAAGTGTCGGGCTATGTCAGTTTACCA
GAGTTGACACGCGCCAACCGCAATTATATGACCATTTTAATCAATGGACGCTACATTAAAAATTTCTTGCTCAATCGGGC
TATTTTAGATGGTTACGGCTCTAAGTTGATGGTTGGACGTTTCCCAATTGTGGTGATTGATATTCAGATTGACCCCTATT
TGGCCGATGTCAATGTTCACCCTACTAAGCAAGAGGTCCGTATTTCAAAAGAGCGTGAGTTGATGGCTTTAATTAGTACG
GCGATTTCTGAAAGTCTTAAGGAGCAAGATTTGATTCCAGATGCTCTGGAGAACTTAGCTAAATCAAGCACACGACACTT
TTCTAAACCAGAGCAAACACAACTTCCATTACAATCTAAAGGGCTTTATTATGATCCTCAAAGAAATGACTTTTTTGTTA
AAGAATCGGATGTTTCTGAAAAAATACCTGAGAGCAATTTTCATAATACAGAGATTGACAAGACTGTAAAGGATCAAAGG
ACGGAGCAGTTTCCTGATTTAGGAGAGAATACAGGATTTTCCTCAGTAAAACGTGCTAGTCGATCACAGGATGAGATAAC
TGATGCTGATCACCCTGGATTTGATTTGAAAAACAAACAGAAATTATCTCAAATGCTAACCCGTTTGGAAAATGAAGAGC
AATCAGTATTTCCCGAATTGGATTATTTTGGTCAGATGCACGGAACTTATCTCTTTGCTCAGGGAAAAGATGGTTTATTT
ATCATTGACCAACACGCTGCCCAAGAGCGGGTTAAATACGAATATTATCGTGATAAGATAGGTGAGGTTGACAGTAGTTT
ACAGCAGCTGTTGGTGCCCTATTTGTTTGAGTTTTCCGGCTCGGATTTCATTAACTTACAGGAGAAAATGGCACTCTTAA
ATGAAGTTGGTATCTTCCTAGAAGTTTATGGGCACAATACTTTCATTTTGAGAGAGCATCCTATCTGGATGAAAGAAGAA
GAGATTGCATCTGGTGTCTATGAAATGTGTGACATGTTACTTCTAACCAATGAGGTCTCTATCAAAACTTACCGAGCAGA
GTTAGCTATTATGATGAGTTGTAAACGATCTATCAAGGCAAATCATAGCTTGGATGATTATTCAGCAAGAAATCTGCTAC
TGCAATTAGCCCAATGTCAAAATCCTTATAACTGCCCTCATGGTAGACCCGTGTTGATTAATTTCAGTAAGGCAGATATG
GAAAAAATGTTCCGTCGTATCCAAGAAAATCATACTAGCCTGCGAGAGCTAGGAAAATATTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

MutL C terminal dimerisation domain (MutL_C)

(462-604)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

67.862

100

0.688

Multiple sequence alignment