Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D9K49_RS16850 Genome accession   NZ_CP036202
Coordinates   3480149..3481981 (+) Length   610 a.a.
NCBI ID   WP_001283421.1    Uniprot ID   P0A8G1
Organism   Escherichia coli strain L725     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3475149..3486981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9K49_RS16815 (D9K49_16815) dcyD 3475376..3476362 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  D9K49_RS16820 (D9K49_16820) tcyL 3476377..3477045 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  D9K49_RS16825 (D9K49_16825) tcyN 3477042..3477794 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  D9K49_RS16830 (D9K49_16830) sdiA 3478024..3478746 (+) 723 WP_001154279.1 transcriptional regulator SdiA -
  D9K49_RS16835 (D9K49_16835) yecF 3478813..3479037 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  D9K49_RS16840 (D9K49_16840) yecU 3479024..3479200 (-) 177 WP_000590347.1 protein YecU -
  D9K49_RS25980 - 3479283..3479354 (-) 72 Protein_3268 transcriptional regulator -
  D9K49_RS16845 (D9K49_16845) letA 3479496..3480152 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  D9K49_RS16850 (D9K49_16850) uvrC 3480149..3481981 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  D9K49_RS16855 (D9K49_16855) pgsA 3482038..3482586 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  D9K49_RS16875 (D9K49_16875) yecA 3483235..3483900 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  D9K49_RS16880 (D9K49_16880) tyrP 3483962..3485173 (-) 1212 WP_000797560.1 tyrosine transporter TyrP -
  D9K49_RS16885 (D9K49_16885) yecH 3485364..3485603 (+) 240 WP_000377225.1 YecH family metal-binding protein -
  D9K49_RS16890 (D9K49_16890) ftnA 3485641..3486138 (-) 498 WP_000917208.1 non-heme ferritin -
  D9K49_RS16895 (D9K49_16895) yecR 3486309..3486632 (-) 324 WP_001237866.1 YecR-like lipofamily protein -
  D9K49_RS16900 (D9K49_16900) azuC 3486895..3486981 (+) 87 WP_010723106.1 stress response protein AzuC -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68188.03 Da        Isoelectric Point: 9.3685

>NTDB_id=306859 D9K49_RS16850 WP_001283421.1 3480149..3481981(+) (uvrC) [Escherichia coli strain L725]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=306859 D9K49_RS16850 WP_001283421.1 3480149..3481981(+) (uvrC) [Escherichia coli strain L725]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATGTCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATCCAGCAAATTGATGTAACGGTTACTCACACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCATATCCTTTTATCTTCCT
GAGTGGTGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACACTGGCGCTACTACAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATACCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGTCGTA
TGGAAACTGCCAGCCAGAATCTGGAGTTTGAAGAAGCTGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAGTTTGTTTCCAATACCGGCGACGACCTCGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGCCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGACTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGTGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACTGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TCGACGACAGTAAGATCCCGGATGTGATACTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGAGCAGATCGTAAGGCTGGGCTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTCAGTTTGCCGCCAGATTCTCCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAGGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGCCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0A8G1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.891

99.508

0.377
  uvrC Streptococcus pneumoniae R6

37.562

99.508

0.374
  uvrC Streptococcus pneumoniae D39

37.562

99.508

0.374

Multiple sequence alignment