Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   DWG18_RS00925 Genome accession   NZ_CP031413
Coordinates   185397..186827 (-) Length   476 a.a.
NCBI ID   WP_115644647.1    Uniprot ID   A0A345ZGW5
Organism   Lysobacter sp. TY2-98     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 171956..184723 185397..186827 flank 674


Gene organization within MGE regions


Location: 171956..186827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DWG18_RS00860 (DWG18_00860) - 171956..172807 (+) 852 WP_115644635.1 glycosyltransferase family 2 protein -
  DWG18_RS00865 (DWG18_00865) - 172869..173942 (+) 1074 WP_162823628.1 glycosyltransferase family 4 protein -
  DWG18_RS00870 (DWG18_00870) - 173982..174893 (-) 912 WP_162823629.1 glycosyltransferase -
  DWG18_RS00875 (DWG18_00875) - 175068..175808 (-) 741 WP_115644638.1 glycosyltransferase family 2 protein -
  DWG18_RS00880 (DWG18_00880) - 175805..177013 (-) 1209 WP_162823630.1 glycosyltransferase -
  DWG18_RS00885 (DWG18_00885) - 177010..177657 (-) 648 WP_115644640.1 DapH/DapD/GlmU-related protein -
  DWG18_RS00890 (DWG18_00890) - 177654..178751 (-) 1098 WP_115644641.1 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme -
  DWG18_RS00895 (DWG18_00895) - 178761..180110 (-) 1350 WP_115644642.1 oligosaccharide flippase family protein -
  DWG18_RS00900 (DWG18_00900) - 180107..181045 (-) 939 WP_115644643.1 GDP-L-fucose synthase -
  DWG18_RS00905 (DWG18_00905) gmd 181050..182159 (-) 1110 WP_115644644.1 GDP-mannose 4,6-dehydratase -
  DWG18_RS00910 (DWG18_00910) - 182474..182554 (-) 81 Protein_178 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  DWG18_RS00915 (DWG18_00915) - 182867..184672 (-) 1806 WP_115644645.1 hypothetical protein -
  DWG18_RS15635 (DWG18_00920) - 184804..185157 (-) 354 WP_115644646.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  DWG18_RS00925 (DWG18_00925) pilR 185397..186827 (-) 1431 WP_115644647.1 sigma-54 dependent transcriptional regulator Regulator

Sequence

Protein


Download         Length: 476 a.a.        Molecular weight: 51302.74 Da        Isoelectric Point: 6.5140

>NTDB_id=306559 DWG18_RS00925 WP_115644647.1 185397..186827(-) (pilR) [Lysobacter sp. TY2-98]
MAEPRSAPARTALVVDDERDIRELLVMTLGRMGLRCDTAANVTDARALLSRNKYDLCLTDMRLPDGTGLEIVSEINSKHP
TTPVAMITAFGNVEAAVEALKAGAFDFVSKPVDLGVLRDLVKQALELHERRRAASEAGISSRLFGESPAMASLRATLTKV
ARSQAPVYISGESGVGKELVARTIHAEGGRASGPFVPVNCGAIPAELMESEFFGHKKGSFTGAHADKPGLFQAADGGTLF
LDEVAELPLPMQVKLLRAIQEKSIRPVGSNNEVKVDVRILSATHKDLAALVEEGRFRHDLYYRINVIELRVPPLRDRPED
LPGLADVILRRLAAAQDRVIPHLSSDAVEALHAYPFPGNVRELENILERALALAEGETIESDDLSLPKSAPKPAPPATPA
APAAAPPPAAPAAADPRNLDPRDTATSALPSYIEEIERAAIQHALQENRYNKTRTAAALGITFRALRYKLKKLGIE

Nucleotide


Download         Length: 1431 bp        

>NTDB_id=306559 DWG18_RS00925 WP_115644647.1 185397..186827(-) (pilR) [Lysobacter sp. TY2-98]
ATGGCCGAACCCCGTAGCGCACCCGCCCGCACCGCCCTTGTCGTGGATGACGAGCGCGACATCCGCGAATTGCTGGTCAT
GACCCTCGGCCGTATGGGCCTGCGCTGCGATACGGCGGCGAACGTCACCGACGCCCGCGCCCTGCTCTCCCGCAACAAAT
ACGACCTCTGCCTGACCGACATGCGGCTGCCCGACGGCACCGGGCTCGAGATCGTTTCCGAGATCAATTCGAAGCACCCG
ACCACGCCGGTCGCCATGATCACGGCCTTCGGCAACGTCGAGGCCGCGGTCGAGGCGCTGAAGGCCGGTGCGTTCGACTT
CGTCAGCAAGCCGGTCGACCTCGGCGTGCTGCGCGACCTGGTCAAGCAGGCGCTGGAACTCCACGAACGCCGCCGCGCCG
CCAGCGAAGCCGGCATCTCGTCGCGCCTGTTCGGCGAATCACCGGCCATGGCCTCGCTGCGCGCCACGCTCACCAAGGTC
GCCCGCAGTCAGGCGCCGGTCTACATCTCCGGCGAATCGGGCGTCGGCAAGGAGCTCGTCGCGCGCACGATCCACGCGGA
GGGTGGACGCGCCTCCGGGCCGTTCGTGCCGGTGAATTGCGGCGCGATTCCCGCCGAACTCATGGAGAGCGAGTTCTTCG
GCCATAAGAAGGGCAGCTTCACCGGCGCCCATGCCGACAAGCCCGGCCTGTTCCAGGCGGCCGACGGTGGCACCCTCTTC
CTCGACGAGGTCGCCGAGCTGCCGCTGCCGATGCAGGTCAAGCTGCTGCGCGCGATCCAGGAGAAGTCGATCCGCCCGGT
CGGCTCGAACAACGAGGTCAAGGTCGACGTCCGCATCCTGTCGGCGACGCACAAGGACCTCGCGGCGCTGGTGGAGGAGG
GCCGCTTCCGCCACGACCTCTACTACCGCATCAACGTCATCGAGCTGCGCGTCCCGCCGCTGCGCGACCGCCCGGAAGAC
CTGCCGGGTCTGGCCGACGTCATCCTCCGCCGCCTTGCAGCCGCCCAGGATCGGGTCATCCCGCACCTGTCGTCCGACGC
GGTCGAGGCGCTGCACGCCTATCCGTTCCCCGGCAACGTCCGTGAACTCGAGAACATCCTGGAGCGCGCGCTCGCGCTGG
CCGAAGGCGAGACGATCGAGTCCGACGACCTGAGCCTGCCCAAGTCGGCCCCGAAGCCGGCGCCACCGGCGACTCCTGCC
GCGCCCGCAGCCGCGCCGCCGCCGGCCGCCCCGGCGGCGGCCGATCCGCGCAACCTCGATCCCCGCGACACCGCGACCAG
CGCGCTGCCGTCGTACATCGAGGAAATCGAGCGCGCCGCGATCCAGCACGCGCTGCAGGAAAACCGCTACAACAAGACTC
GGACCGCCGCGGCCCTTGGCATCACCTTCCGGGCCCTGCGGTACAAGTTGAAGAAACTGGGGATCGAATAA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(144-309)

Bacterial regulatory protein, Fis family (HTH_8)

(433-473)

Response regulator receiver domain (Response_reg)

(13-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345ZGW5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

61.242

98.109

0.601
  pilR Acinetobacter baumannii strain A118

47.974

98.529

0.473

Multiple sequence alignment