Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EW995_RS09995 Genome accession   NZ_CP035884
Coordinates   2050251..2050883 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain LSN03-016011/A     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2045251..2055883
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW995_RS09970 yheS 2045420..2047333 (+) 1914 WP_000634789.1 ABC transporter ATP-binding protein -
  EW995_RS09975 yheT 2047333..2048355 (+) 1023 WP_000057380.1 hydrolase -
  EW995_RS09980 yheU 2048349..2048567 (+) 219 WP_000907085.1 YheU family protein -
  EW995_RS09985 prkB 2048621..2049490 (+) 870 WP_001274680.1 phosphoribulokinase -
  EW995_RS09990 yhfA 2049545..2049949 (-) 405 WP_001148908.1 OsmC family protein -
  EW995_RS09995 crp 2050251..2050883 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EW995_RS10000 yhfK 2050934..2053024 (+) 2091 WP_001309001.1 YccS/YhfK family putative transporter -
  EW995_RS10005 argD 2053091..2054311 (-) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EW995_RS10010 pabA 2054397..2054960 (-) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  EW995_RS10015 fic 2054992..2055594 (-) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EW995_RS10020 yhfG 2055584..2055751 (-) 168 WP_000736862.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=306460 EW995_RS09995 WP_000242755.1 2050251..2050883(+) (crp) [Escherichia coli strain LSN03-016011/A]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=306460 EW995_RS09995 WP_000242755.1 2050251..2050883(+) (crp) [Escherichia coli strain LSN03-016011/A]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment