Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EW997_RS24740 Genome accession   NZ_CP035879
Coordinates   5050554..5051210 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain DS26-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5045554..5056210
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW997_RS24710 dcyD 5046433..5047419 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  EW997_RS24715 tcyL 5047434..5048102 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EW997_RS24720 tcyN 5048099..5048851 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EW997_RS24725 sdiA 5049081..5049803 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  EW997_RS24730 yecF 5049871..5050095 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EW997_RS24735 yecU 5050082..5050258 (-) 177 WP_000590347.1 protein YecU -
  EW997_RS26725 - 5050341..5050412 (-) 72 Protein_4866 transcriptional regulator -
  EW997_RS24740 letA 5050554..5051210 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EW997_RS24745 uvrC 5051207..5053039 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EW997_RS24750 pgsA 5053096..5053644 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EW997_RS24770 - 5054638..5054919 (+) 282 WP_071595684.1 hypothetical protein -
  EW997_RS24775 - 5055109..5055248 (-) 140 Protein_4871 Hok/Gef family protein -
  EW997_RS24780 - 5055438..5055698 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=306345 EW997_RS24740 WP_000611335.1 5050554..5051210(+) (letA) [Escherichia coli strain DS26-1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=306345 EW997_RS24740 WP_000611335.1 5050554..5051210(+) (letA) [Escherichia coli strain DS26-1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486