Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EW998_RS10850 Genome accession   NZ_CP035874
Coordinates   2271804..2272460 (+) Length   218 a.a.
NCBI ID   WP_000611338.1    Uniprot ID   -
Organism   Escherichia coli strain B2C     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2266804..2277460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW998_RS10820 dcyD 2267683..2268669 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  EW998_RS10825 tcyL 2268684..2269352 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  EW998_RS10830 tcyN 2269349..2270101 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  EW998_RS10835 sdiA 2270331..2271053 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  EW998_RS10840 yecF 2271121..2271345 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  EW998_RS10845 yecU 2271332..2271508 (-) 177 WP_001302050.1 protein YecU -
  EW998_RS26300 - 2271546..2271662 (-) 117 WP_001302039.1 hypothetical protein -
  EW998_RS10850 letA 2271804..2272460 (+) 657 WP_000611338.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  EW998_RS10855 uvrC 2272457..2274289 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  EW998_RS10860 pgsA 2274346..2274894 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  EW998_RS10880 - 2275889..2276170 (+) 282 WP_071529678.1 hypothetical protein -
  EW998_RS10885 - 2276360..2276500 (-) 141 WP_000078920.1 Hok/Gef family protein -
  EW998_RS10890 - 2276690..2276950 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23908.65 Da        Isoelectric Point: 6.9614

>NTDB_id=306239 EW998_RS10850 WP_000611338.1 2271804..2272460(+) (letA) [Escherichia coli strain B2C]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNSVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=306239 EW998_RS10850 WP_000611338.1 2271804..2272460(+) (letA) [Escherichia coli strain B2C]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGCGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATTCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGCAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGTGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.691

94.954

0.491
  letA Legionella pneumophila strain ERS1305867

51.691

94.954

0.491

Multiple sequence alignment