Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   SPCG_RS08040 Genome accession   NC_010582
Coordinates   1524951..1526183 (-) Length   410 a.a.
NCBI ID   WP_000106354.1    Uniprot ID   A0A4M6D977
Organism   Streptococcus pneumoniae CGSP14     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1519951..1531183
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPCG_RS08010 (SPCG_1548) - 1520141..1521106 (+) 966 WP_000081011.1 NAD(P)/FAD-dependent oxidoreductase -
  SPCG_RS08015 (SPCG_1549) whiA 1521140..1522051 (-) 912 WP_000011276.1 DNA-binding protein WhiA -
  SPCG_RS08020 (SPCG_1550) - 1522048..1523025 (-) 978 WP_001231086.1 YvcK family protein -
  SPCG_RS08025 (SPCG_1551) rapZ 1523022..1523912 (-) 891 WP_000163035.1 RNase adapter RapZ -
  SPCG_RS08030 (SPCG_1552) - 1523964..1524344 (-) 381 WP_001140412.1 RidA family protein -
  SPCG_RS08035 (SPCG_1553) yihA 1524355..1524942 (-) 588 WP_000422605.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  SPCG_RS08040 (SPCG_1554) clpX 1524951..1526183 (-) 1233 WP_000106354.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  SPCG_RS08045 (SPCG_1555) - 1526215..1526385 (-) 171 WP_000442276.1 hypothetical protein -
  SPCG_RS08050 (SPCG_1556) - 1526385..1526891 (-) 507 WP_000162437.1 dihydrofolate reductase -
  SPCG_RS08055 (SPCG_1557) - 1527021..1527539 (-) 519 WP_000229856.1 DNA starvation/stationary phase protection protein -
  SPCG_RS08060 (SPCG_1559) lytC 1528037..1529542 (-) 1506 WP_012386833.1 choline binding-anchored murein hydrolase LytC -
  SPCG_RS08065 (SPCG_1560) tpiA 1529580..1530338 (-) 759 WP_000087907.1 triose-phosphate isomerase -
  SPCG_RS08070 (SPCG_1561) - 1530436..1531113 (-) 678 WP_000221614.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45713.24 Da        Isoelectric Point: 4.4550

>NTDB_id=30621 SPCG_RS08040 WP_000106354.1 1524951..1526183(-) (clpX) [Streptococcus pneumoniae CGSP14]
MSTNRKNDMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=30621 SPCG_RS08040 WP_000106354.1 1524951..1526183(-) (clpX) [Streptococcus pneumoniae CGSP14]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAGCCAAGAAGAAGTACAAAAAATAAT
CGCTGGCAACAATGCCTTTATTTGTAATGAATGCGTGGAGCTAGCTCAAGAAATTATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTACCAAAACCAATCGAACTCCTCCATATCTTGAACCACTATGTAATCGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAATCATTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATCTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCTCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCGATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTAGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGCTGCTGACTTTAACATTGAGCGTGCAGAACGTGGGATTATCTACGTGGATGAAATTGA
CAAGATTGCTAAAAAGAGCGAGAATGTATCGATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTCCTCAAGA
TTATCGAGGGAACCGTCGCAAGCGTACCTCCTCAAGGTGGTCGCAAGCATCCACAACAAGAGATGATTCAAGTGGATACT
AAAAATATCCTCTTTATCGTGGGTGGTGCCTTTGATGGCATTGAAGAAATCGTCAAACAACGTCTTGGAGAAAAAGTCAT
CGGATTTGGTCAAAATAACAAGGCGATTGATGAAAACAGCTCTTACATGCAAGAAATCATCGCAGAGGATATTCAAAAAT
TTGGTATTATCCCTGAGTTAATTGGACGCTTGCCTGTTTTTGCTGCTCTTGAGCAATTGACGGTCGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTCAAACAGTACCAAACCTTGCTTTCTTATGATGATGTCGAGTTGGAATTTGA
CGACGAAGCCCTACAAGAGATTGCTAATAAAGCCATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCTATTATCGAAG
AAACAATGCTAGATGTCATGTTTGAAGTACCGAGTCAGGAAAATGTGAAATTGGTCCGCATCACTAAAGAAGCTGTTGAT
GGAACGGATAAACCAATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4M6D977

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.829

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.463

98.049

0.563

Multiple sequence alignment